SCHEMBL31337844

SCHEMBL31337844

O=C(O)/C=C/C1=CC(=O)CC1

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HCAR2 Q8TDS4 5/20 0.39
HDAC3 O15379 2/20 0.39
HDAC4 P56524 2/20 0.39
HDAC1 Q13547 2/20 0.39
HDAC7 Q8WUI4 2/20 0.39
HDAC2 Q92769 2/20 0.39
HDAC10 Q969S8 2/20 0.39
HDAC11 Q96DB2 2/20 0.39
HDAC8 Q9BY41 2/20 0.39
HDAC6 Q9UBN7 2/20 0.39
HDAC9 Q9UKV0 2/20 0.39
HDAC5 Q9UQL6 2/20 0.39
TNKS O95271 1/20 0.39
TNKS2 Q9H2K2 1/20 0.39
CA1 P00915 3/20 0.36
CA2 P00918 3/20 0.36
CA4 P22748 3/20 0.36
PKM P14618 2/20 0.36
CA12 O43570 2/20 0.36
AKR1B10 O60218 2/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10535448 0.77 IAPP (0.40) ALDH1A1CYP3A4TDP1TSHRALOX15
SCHEMBL10535453 0.77 IAPP (0.40) ALDH1A1CYP3A4TDP1TSHRALOX15
SCHEMBL19261683 0.71
SCHEMBL10378479 0.71
SCHEMBL4264349 0.71 HCAR2 (0.44) HCAR2HDAC3HDAC4HDAC1HDAC7
SCHEMBL4270776 0.71 HCAR2 (0.44) HCAR2HDAC3HDAC4HDAC1HDAC7
SCHEMBL19868544 0.69 HCAR2 (0.39) HCAR2HDAC3HDAC4HDAC1HDAC7
SCHEMBL125455 0.67
SCHEMBL28876118 0.67 HCAR2 (0.35) HCAR2HDAC3HDAC4HDAC1HDAC7
SCHEMBL4188530 0.67 HCAR2 (0.39) HCAR2HDAC3HDAC4HDAC1HDAC7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119081877-A Marine fungus Trichoderma and quorum sensing inhibitor alpha, beta-unsaturated cyclopentanone compound, and preparation method and application thereof 广东工业大学 2024-12-06 CN claimed
CN-119081877-A Marine fungus Trichoderma and quorum sensing inhibitor alpha, beta-unsaturated cyclopentanone compound, and preparation method and application thereof 广东工业大学 2024-12-06 CN disclosed
CN-119081877-A Marine fungus Trichoderma and quorum sensing inhibitor alpha, beta-unsaturated cyclopentanone compound, and preparation method and application thereof 广东工业大学 2024-12-06 CN disclosed