SCHEMBL4188530

SCHEMBL4188530

O=C(O)C=CC1=CCCC1

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HCAR2 Q8TDS4 5/20 0.39
HDAC3 O15379 3/20 0.39
HDAC4 P56524 3/20 0.39
HDAC1 Q13547 3/20 0.39
HDAC7 Q8WUI4 3/20 0.39
HDAC2 Q92769 3/20 0.39
HDAC8 Q9BY41 3/20 0.39
HDAC6 Q9UBN7 3/20 0.39
HDAC5 Q9UQL6 3/20 0.39
HDAC10 Q969S8 2/20 0.39
HDAC11 Q96DB2 2/20 0.39
HDAC9 Q9UKV0 2/20 0.39
TNKS O95271 1/20 0.39
TNKS2 Q9H2K2 1/20 0.39
TAAR1 Q96RJ0 1/20 0.38
CA1 P00915 3/20 0.36
CA2 P00918 3/20 0.36
CA4 P22748 3/20 0.36
CA12 O43570 2/20 0.36
AKR1B10 O60218 2/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9474747 1.00 HCAR2 (0.39) HCAR2HDAC3HDAC4HDAC1HDAC7
SCHEMBL4195192 0.94 TAAR1 (0.44) HCAR2HDAC3HDAC4HDAC1HDAC7
SCHEMBL471180 0.94 TAAR1 (0.44) HCAR2HDAC3HDAC4HDAC1HDAC7
SCHEMBL2787551 0.92 TAAR1 (0.43) HCAR2HDAC3HDAC4HDAC1HDAC7
SCHEMBL4190776 0.92 TAAR1 (0.43) HCAR2HDAC3HDAC4HDAC1HDAC7
SCHEMBL7353784 0.92 TAAR1 (0.43) HCAR2HDAC3HDAC4HDAC1HDAC7
SCHEMBL7353792 0.92 TAAR1 (0.43) HCAR2HDAC3HDAC4HDAC1HDAC7
SCHEMBL7353777 0.92 TAAR1 (0.43) HCAR2HDAC3HDAC4HDAC1HDAC7
SCHEMBL9578841 0.87 TAAR1 (0.40) HCAR2HDAC3HDAC4HDAC1HDAC7
SCHEMBL10378479 0.85

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4042648-A Olefin-acrylic ester copolymer-thermoplastic resin composition SUMITOMO CHEMICAL COMPANY, LIMITED (JA) 1977-08-16 US claimed
US-4001159-A Aqueous dispersion of olefin-acrylate copolymer SUMITOMO CHEMICAL COMPANY, LIMITED (JA) 1977-01-04 US claimed
US-4000958-A Method for treating leather SUMITOMO CHEMICAL COMPANY, LIMITED (JA) 1977-01-04 US claimed
US-3957732-A ALTERNATING COPOLYMERS HAVING FUNCTIONAL GROUP AND PROCESS FOR PRODUCING SAME SUMITOMO CHEMICAL COMPANY, LIMITED (JA) 1976-05-18 US claimed
US-20220340893-A1 BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES NUEVOLUTION A/S (DK) 2022-10-27 US disclosed
US-20090092975-A1 SELECTABLE MARKER MOLOGIC LTD (GB) 2009-04-09 US disclosed
US-20030013830-A1 Reacting a thiosulfate salt with a halogenated styrenic monomer to form a styrenic thiosulfate salt monomer and then polymerization of said monomer in the presence of an initiator BLEVINS RICHARD W (US) 2003-01-16 US disclosed
US-6420505-B1 STYRENE THIOSULFATE AND OLEFIN MONOMER EASTMAN KODAK COMPANY 2002-07-16 US disclosed
WO-1993013062-A1 HALOGENATED TETRAENYL PROSTAGLANDIN DERIVATIVES G.D. SEARLE & CO. (US) 1993-07-08 WO disclosed
US-5177251-A Cytoprotective, antisecretory, side effect reduction G. D. SEARLE & CO. (US) 1993-01-05 US disclosed
EP-0164270-A2 Photo-polymerizable compositon and printing plate prepared therefrom NAPP SYSTEMS INC. (US) 1985-12-11 EP disclosed
US-4042648-A Olefin-acrylic ester copolymer-thermoplastic resin composition SUMITOMO CHEMICAL COMPANY, LIMITED (JA) 1977-08-16 US disclosed
US-4001159-A Aqueous dispersion of olefin-acrylate copolymer SUMITOMO CHEMICAL COMPANY, LIMITED (JA) 1977-01-04 US disclosed
US-4000958-A Method for treating leather SUMITOMO CHEMICAL COMPANY, LIMITED (JA) 1977-01-04 US disclosed
US-3957732-A ALTERNATING COPOLYMERS HAVING FUNCTIONAL GROUP AND PROCESS FOR PRODUCING SAME SUMITOMO CHEMICAL COMPANY, LIMITED (JA) 1976-05-18 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090092975-A1 SELECTABLE MARKER AMD1, PADI1, PSAT1 HCAR2 826/4885HDAC3 3610/4885HDAC4 2929/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.