SCHEMBL31338686

SCHEMBL31338686

CCCc1ccc(-c2cn3c(n2)sc2cc(S(C)(=O)=O)ccc23)cc1

nearest known ligand 0.51

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
TP53 P04637 6/20 0.51
LMNA P02545 5/20 0.50
RXFP1 Q9HBX9 1/20 0.48
MAPT P10636 5/20 0.48
THRB P10828 3/20 0.47
TSHR P16473 1/20 0.46
RAB9A P51151 1/20 0.46
ATM Q13315 1/20 0.46
SMN1; SMN2 Q16637 1/20 0.46
TDP1 Q9NUW8 1/20 0.46
APP P05067 1/20 0.45
KDM4E B2RXH2 1/20 0.44
ALDH1A1 P00352 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24106018 0.84 CA12 (0.52) TP53LMNARXFP1MAPTTSHR
SCHEMBL31338687 0.84 MAPT (0.53) TP53LMNARXFP1MAPTTHRB
SCHEMBL31236166 0.84 TP53 (0.63) TP53LMNARXFP1MAPTTHRB
SCHEMBL24106081 0.84 TP53 (0.63) TP53LMNARXFP1MAPTTHRB
SCHEMBL31338708 0.84 MAPT (0.67) TP53LMNARXFP1MAPTTHRB
SCHEMBL31338707 0.83 TP53 (0.65) TP53LMNARXFP1MAPTTHRB
SCHEMBL31338693 0.82 LMNA (0.47) TP53LMNARXFP1MAPTTHRB
SCHEMBL31338669 0.81 CA12 (0.46) TP53LMNARXFP1MAPTTSHR
SCHEMBL31338678 0.77 TP53 (0.49) TP53LMNARXFP1MAPTTHRB
SCHEMBL31338689 0.77 TP53 (0.65) TP53LMNARXFP1MAPTTHRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4741401-A1 BENZOTHIAZOIMIDAZOLYL COMPOUND AND USE THEREOF ER Stress Research Institute, Inc. (JP) 2026-05-13 EP disclosed
WO-2025009553-A1 BENZOTHIAZOIMIDAZOLYL COMPOUND AND USE THEREOF 小胞体ストレス研究所株式会社 2025-01-09 WO disclosed