Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 4/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.38 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.38 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.38 |
| ▸ | FLT1 | P17948 | 1/20 | 0.38 |
| ▸ | FGFR3 | P22607 | 1/20 | 0.38 |
| ▸ | KDR | P35968 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 3/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | GBA1 | P04062 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1191026 | 1.00 | PTGS2 (0.40) | PTGS2MAPTGAAPDGFRBFGFR1 | |
| SCHEMBL751950 | 0.87 | LMNA (0.41) | MAPTGAALMNATSHRSMN1; SMN2 | |
| SCHEMBL30046816 | 0.87 | LMNA (0.41) | MAPTGAALMNATSHRSMN1; SMN2 | |
| SCHEMBL2685199 | 0.86 | AAK1 (0.41) | MAPTGAALMNASMN1; SMN2CYP1A2 | |
| SCHEMBL1190428 | 0.85 | SMN1; SMN2 (0.46) | PTGS2MAPTPDGFRBFGFR1PDGFRA | |
| SCHEMBL2686001 | 0.85 | MEN1 (0.43) | MAPTSMN1; SMN2CYP1A2ALDH1A1NPC1 | |
| SCHEMBL2685997 | 0.85 | MEN1 (0.43) | MAPTSMN1; SMN2CYP1A2ALDH1A1NPC1 | |
| SCHEMBL1191402 | 0.84 | PTGS2 (0.40) | PTGS2MAPTPDGFRBFGFR1PDGFRA | |
| SCHEMBL5309167 | 0.83 | MAPT (0.51) | PTGS2MAPTPDGFRBFGFR1PDGFRA | |
| SCHEMBL15889718 | 0.83 | MAPT (0.40) | PTGS2MAPTGAAPDGFRBFGFR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119110803-A | Novel bicyclic substituted sulfonylurea compounds as inhibitors of interleukin-1 activity | 唯久生物技术(苏州)有限公司 | 2024-12-10 | — | — | CN | disclosed |