Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.49 |
| ▸ | HTT | P42858 | 3/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.49 |
| ▸ | CES2 | O00748 | 1/20 | 0.49 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | GLA | P06280 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.49 |
| ▸ | AR | P10275 | 1/20 | 0.49 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.49 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.49 |
| ▸ | AADAC | P22760 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21461509 | 1.00 | ALDH1A1 (0.49) | ALDH1A1SMN1; SMN2HTTLMNAMAPK1 | |
| SCHEMBL29176025 | 0.87 | TDP1 (0.40) | ALDH1A1SMN1; SMN2HTTLMNAMAPK1 | |
| SCHEMBL10129571 | 0.84 | GAA (0.46) | ALDH1A1SMN1; SMN2HTTLMNAMAPK1 | |
| SCHEMBL25343054 | 0.82 | ALDH1A1 (0.45) | ALDH1A1SMN1; SMN2HTTLMNAMAPK1 | |
| SCHEMBL21681166 | 0.81 | TSHR (0.47) | ALDH1A1SMN1; SMN2LMNATSHRKMT2A | |
| SCHEMBL25429447 | 0.81 | HTT (0.41) | ALDH1A1SMN1; SMN2HTTLMNAMAPK1 | |
| SCHEMBL25428522 | 0.79 | TDP1 (0.40) | ALDH1A1SMN1; SMN2HTTLMNAMAPK1 | |
| SCHEMBL8407132 | 0.78 | ALDH1A1 (0.49) | ALDH1A1SMN1; SMN2HTTLMNAMAPK1 | |
| SCHEMBL25341037 | 0.77 | PKM (0.50) | ALDH1A1SMN1; SMN2HTTLMNAMAPK1 | |
| SCHEMBL25429125 | 0.77 | KMT2A (0.48) | ALDH1A1LMNAMAPK1TSHRKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119365192-A | Heteroaryl compounds as HPK1 inhibitors and methods of use thereof | 深圳市原力深湾创新药有限公司 | 2025-01-24 | — | — | CN | disclosed |