Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BACE1 | P56817 | 1/20 | 0.46 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.46 |
| ▸ | TLR2 | O60603 | 2/20 | 0.43 |
| ▸ | TLR1 | Q15399 | 2/20 | 0.43 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.40 |
| ▸ | F10 | P00742 | 1/20 | 0.40 |
| ▸ | NAMPT | P43490 | 1/20 | 0.39 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.39 |
| ▸ | MMP3 | P08254 | 1/20 | 0.39 |
| ▸ | MMP7 | P09237 | 1/20 | 0.39 |
| ▸ | MMP10 | P09238 | 1/20 | 0.39 |
| ▸ | MMP8 | P22894 | 1/20 | 0.39 |
| ▸ | MMP12 | P39900 | 1/20 | 0.39 |
| ▸ | TACR1 | P25103 | 1/20 | 0.39 |
| ▸ | IDO1 | P14902 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6344562 | 1.00 | BACE1 (0.46) | BACE1USP30TLR2TLR1MDM2 | |
| SCHEMBL7205505 | 0.92 | BACE1 (0.45) | BACE1USP30TLR2TLR1KMT2A | |
| SCHEMBL6353989 | 0.92 | BACE1 (0.45) | BACE1USP30TLR2TLR1KMT2A | |
| SCHEMBL21319696 | 0.89 | BACE1 (0.46) | BACE1USP30TLR2TLR1MDM2 | |
| SCHEMBL12164667 | 0.88 | BACE1 (0.44) | BACE1USP30TLR2TLR1MDM2 | |
| SCHEMBL6349287 | 0.87 | BACE1 (0.45) | BACE1USP30TLR2TLR1MDM2 | |
| SCHEMBL25355246 | 0.86 | BACE1 (0.46) | BACE1USP30MDM2KMT2ANAMPT | |
| SCHEMBL14678450 | 0.85 | BACE1 (0.46) | BACE1USP30TLR2TLR1MDM2 | |
| SCHEMBL29569298 | 0.85 | BACE1 (0.46) | BACE1USP30TLR2TLR1MDM2 | |
| SCHEMBL148055 | 0.84 | BACE1 (0.42) | BACE1USP30TLR2TLR1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8772450-B2 | Beta-amino acids | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 2014-07-08 | — | — | US | disclosed |
| US-20130023644-A1 | BETA-AMINO ACIDS | WISCONSIN ALUMNI RESEARCH FOUNDATION | 2013-01-24 | — | — | US | disclosed |
| US-8138168-B1 | Renin inhibitors | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2012-03-20 | — | — | US | disclosed |
| US-8138168-B1 | Renin inhibitors | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2012-03-20 | — | — | US | disclosed |
| US-8138168-B1 | Renin inhibitors | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2012-03-20 | — | — | US | disclosed |
| US-7304165-B2 | Oligomers and polymers of di-substituted cyclic imino carboxylic acids | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 2007-12-04 | — | — | US | disclosed |
| US-20070154882-A1 | Beta-polypeptides that inhibit cytomegalovirus infection | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2007-07-05 | — | — | US | disclosed |
| US-20070123709-A1 | Beta-amino acids | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2007-05-31 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070123709-A1 | Beta-amino acids | BCAT1, MARCKS, YWHAZ | BACE1 441/4885USP30 367/4885TLR2 4190/4885 |
| US-20130023644-A1 | BETA-AMINO ACIDS | BCAT1, MARCKS, YWHAZ | BACE1 441/4885USP30 367/4885TLR2 4190/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.