Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | GHSR | Q92847 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | CNR1 | P21554 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | GFER | P55789 | 1/20 | 0.39 |
| ▸ | STAT3 | P40763 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2004976 | 0.93 | SCD5 (0.43) | KMT2AALDH1A1SMN1; SMN2MAPTHTT | |
| SCHEMBL3055422 | 0.92 | KMT2A (0.47) | KMT2AALDH1A1SMN1; SMN2MAPTHTT | |
| SCHEMBL2012053 | 0.87 | TACR3 (0.47) | CNR1 | |
| SCHEMBL2005920 | 0.87 | TACR3 (0.47) | CNR1 | |
| SCHEMBL2004776 | 0.84 | ALDH1A1 (0.54) | KMT2AALDH1A1SMN1; SMN2MAPTHTT | |
| SCHEMBL2010870 | 0.84 | TACR3 (0.48) | GHSR | |
| SCHEMBL12569344 | 0.83 | CNR1 (0.46) | KMT2AALDH1A1SMN1; SMN2MAPTHTT | |
| SCHEMBL4689255 | 0.82 | TSHR (0.42) | ALDH1A1SMN1; SMN2MAPTHTTGHSR | |
| SCHEMBL2007046 | 0.82 | CNR1 (0.53) | KMT2ASMN1; SMN2HTTKDM4ECNR1 | |
| SCHEMBL2009579 | 0.82 | CNR1 (0.53) | KMT2ASMN1; SMN2HTTKDM4ECNR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1981504-B1 | THIADIAZOLE DERIVATIVES FOR THE TREATMENT OF NEURO DEGENERATIVE DISEASES | REMYND NV (BE) | 2010-07-21 | — | — | EP | claimed |