SCHEMBL3134061

SCHEMBL3134061

CCCCC(=O)NNS(=O)(=O)c1cccc(-c2ccccc2)c1

nearest known ligand 0.62

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.62
GAA P10253 1/20 0.62
HPGD P15428 1/20 0.62
KAT6A Q92794 12/20 0.53
RAB9A P51151 1/20 0.50
KMT2A Q03164 1/20 0.50
POLB P06746 1/20 0.49
CYP2C19 P33261 1/20 0.48
LARS1 Q9P2J5 1/20 0.47
BCAT1 P54687 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3142366 0.88 ALDH1A1 (0.66) ALDH1A1GAAHPGDRAB9AKMT2A
SCHEMBL3171214 0.84 ALDH1A1 (0.71) ALDH1A1GAAHPGDKAT6ARAB9A
SCHEMBL3147276 0.81 KAT6A (0.58) ALDH1A1GAAHPGDKAT6ARAB9A
SCHEMBL13954376 0.75 LARS1 (0.60) KAT6ALARS1
SCHEMBL28676609 0.75 ALDH1A1 (0.85) ALDH1A1GAAHPGDRAB9AKMT2A
SCHEMBL20233085 0.75 KAT6A (0.83) GAAKAT6AKMT2A
SCHEMBL14865509 0.73 ALDH1A1 (0.63) ALDH1A1GAAHPGDRAB9A
SCHEMBL5183973 0.72 KAT6A (0.56) ALDH1A1GAAKAT6AKMT2APOLB
SCHEMBL7449510 0.71 ALDH1A1 (0.52) ALDH1A1GAAKAT6ARAB9AKMT2A
SCHEMBL28692846 0.71 ALDH1A1 (0.88) ALDH1A1GAAHPGDRAB9AKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20100004339-A1 Somatostatin Receptor 1 and/or 4 Selective Agonists and Antagonists OY JUVANTIA PHARMA LTD. (FI) 2010-01-07 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100004339-A1 Somatostatin Receptor 1 and/or 4 Selective Agonists and Antagonists SSTR4, SSTR1, SSTR3 ALDH1A1 4124/4885GAA 2847/4885HPGD 4435/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.