SCHEMBL3147276

SCHEMBL3147276

CCCCC(=O)NNS(=O)(=O)c1ccc2ccccc2c1

nearest known ligand 0.58

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
KAT6A Q92794 12/20 0.58
LMNA P02545 3/20 0.57
ALDH1A1 P00352 3/20 0.56
GAA P10253 2/20 0.56
HPGD P15428 1/20 0.56
RAB9A P51151 2/20 0.55
KMT2A Q03164 1/20 0.55
NPC1 O15118 1/20 0.54
SMN1; SMN2 Q16637 1/20 0.54
KAT7 O95251 1/20 0.53
CYP3A4 P08684 1/20 0.53
CYP2D6 P10635 1/20 0.53
KCNH2 Q12809 1/20 0.53
KAT6B Q8WYB5 1/20 0.53
KAT5 Q92993 1/20 0.53
KAT8 Q9H7Z6 1/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5780621 0.82 KAT6A (0.61) KAT6ALMNAALDH1A1GAAKAT7
SCHEMBL3142366 0.81 ALDH1A1 (0.66) ALDH1A1GAAHPGDRAB9AKMT2A
SCHEMBL3134061 0.81 ALDH1A1 (0.62) KAT6AALDH1A1GAAHPGDRAB9A
SCHEMBL28676609 0.79 ALDH1A1 (0.85) LMNAALDH1A1GAAHPGDRAB9A
SCHEMBL3171214 0.79 ALDH1A1 (0.71) KAT6AALDH1A1GAAHPGDRAB9A
SCHEMBL6633162 0.78 LMNA (0.68) LMNAALDH1A1GAAHPGDRAB9A
SCHEMBL6825949 0.76 KAT6A (0.65) KAT6ALMNAALDH1A1GAASMN1; SMN2
SCHEMBL28692846 0.75 ALDH1A1 (0.88) LMNAALDH1A1GAAHPGDRAB9A
SCHEMBL8684777 0.75 ALDH1A1 (0.48) LMNAALDH1A1GAAHPGDRAB9A
SCHEMBL3685286 0.75 ALDH1A1 (0.68) LMNAALDH1A1GAASMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20100004339-A1 Somatostatin Receptor 1 and/or 4 Selective Agonists and Antagonists OY JUVANTIA PHARMA LTD. (FI) 2010-01-07 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100004339-A1 Somatostatin Receptor 1 and/or 4 Selective Agonists and Antagonists SSTR4, SSTR1, SSTR3 KAT6A 3271/4885LMNA 3980/4885ALDH1A1 4124/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.