Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | UCHL1 | P09936 | 1/20 | 0.53 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.33 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | JAK2 | O60674 | 1/20 | 0.31 |
| ▸ | JAK1 | P23458 | 1/20 | 0.31 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.31 |
| ▸ | HTRA1 | Q92743 | 1/20 | 0.31 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.31 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30501862 | 1.00 | UCHL1 (0.53) | UCHL1NR1H2CYP1A2POLBCYP3A4 | |
| SCHEMBL25619159 | 1.00 | UCHL1 (0.53) | UCHL1NR1H2CYP1A2POLBCYP3A4 | |
| SCHEMBL27393752 | 1.00 | UCHL1 (0.53) | UCHL1NR1H2CYP1A2POLBCYP3A4 | |
| SCHEMBL18538108 | 1.00 | UCHL1 (0.53) | UCHL1NR1H2CYP1A2POLBCYP3A4 | |
| SCHEMBL18577227 | 0.91 | UCHL1 (0.45) | UCHL1NR1H2CYP1A2POLBCYP3A4 | |
| SCHEMBL18577225 | 0.91 | UCHL1 (0.45) | UCHL1NR1H2CYP1A2POLBCYP3A4 | |
| SCHEMBL5359255 | 0.89 | UCHL1 (0.54) | UCHL1NR1H2CYP1A2POLBCYP3A4 | |
| SCHEMBL31573208 | 0.87 | UCHL1 (0.43) | UCHL1NR1H2CYP1A2POLBCYP3A4 | |
| SCHEMBL8212932 | 0.86 | UCHL1 (0.42) | UCHL1NR1H2CYP1A2POLBCYP3A4 | |
| SCHEMBL13103213 | 0.86 | UCHL1 (0.38) | UCHL1NR1H2CYP1A2POLBCYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4747250-A1 | KINASE INHIBITORS | The United States Of America, As Represented By The Secretary, Department of Health and Human Services (US) | 2026-05-27 | — | — | EP | disclosed |
| WO-2025019585-A1 | KINASE INHIBITORS | THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) | 2025-01-23 | — | — | WO | disclosed |