SCHEMBL3134095

SCHEMBL3134095

F/[C]=C/c1ccc(F)cc1

nearest known ligand 0.48

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
HSD11B1 P28845 2/20 0.44
NFE2L2 Q16236 7/20 0.44
APP P05067 1/20 0.38
PTGS1 P23219 1/20 0.38
FBP1 P09467 1/20 0.37
GRIN2D O15399 1/20 0.35
GRIN3B O60391 1/20 0.35
GRIN1 Q05586 1/20 0.35
GRIN2A Q12879 1/20 0.35
GRIN2B Q13224 1/20 0.35
GRIN2C Q14957 1/20 0.35
GRIN3A Q8TCU5 1/20 0.35
TNFRSF1A P19438 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3134885 1.00 HSD11B1 (0.44) HSD11B1NFE2L2APPPTGS1FBP1
SCHEMBL208699 1.00 HSD11B1 (0.44) HSD11B1NFE2L2APPPTGS1FBP1
SCHEMBL3126253 0.76 NFE2L2 (0.46) NFE2L2PTGS1FBP1GRIN2DGRIN3B
SCHEMBL3134562 0.76 HSD17B10 (0.46) NFE2L2FBP1GRIN2DGRIN3BGRIN1
SCHEMBL208020 0.76 HSD17B10 (0.46) NFE2L2FBP1GRIN2DGRIN3BGRIN1
SCHEMBL3126258 0.76 NFE2L2 (0.46) NFE2L2PTGS1FBP1GRIN2DGRIN3B
SCHEMBL206780 0.76 CYP2A6 (0.42)
SCHEMBL14555044 0.76 HSD11B1 (0.43) HSD11B1NFE2L2APPPTGS1FBP1
SCHEMBL3126254 0.76 HSD17B10 (0.46) NFE2L2FBP1GRIN2DGRIN3BGRIN1
SCHEMBL3131905 0.76 NFE2L2 (0.46) NFE2L2PTGS1FBP1GRIN2DGRIN3B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2183213-A2 OPTICALLY ACTIVE (R)-ARYLOXYPROPIONIC ACID AMIDES AND HERBICIDAL COMPOSITION COMPRISING SAME Kyung Nong Corporation (KR) 2010-05-12 EP disclosed
WO-2009005297-A2 OPTICALLY ACTIVE (R)-ARYLOXYPROPIONIC ACID AMIDES AND HERBICIDAL COMPOSITION COMPRISING SAME KYUNG NONG CORPORATION (KR) 2009-01-08 WO disclosed