Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS1 | P29475 | 2/20 | 0.43 |
| ▸ | NOS2 | P35228 | 2/20 | 0.43 |
| ▸ | MAPK7 | Q13164 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 5/20 | 0.42 |
| ▸ | FASN | P49327 | 1/20 | 0.39 |
| ▸ | GRM3 | Q14832 | 1/20 | 0.39 |
| ▸ | MKNK1 | Q9BUB5 | 2/20 | 0.39 |
| ▸ | MKNK2 | Q9HBH9 | 2/20 | 0.39 |
| ▸ | PRKAB2 | O43741 | 2/20 | 0.38 |
| ▸ | PRKAG1 | P54619 | 2/20 | 0.38 |
| ▸ | PRKAA2 | P54646 | 2/20 | 0.38 |
| ▸ | PRKAA1 | Q13131 | 2/20 | 0.38 |
| ▸ | PRKAG3 | Q9UGI9 | 2/20 | 0.38 |
| ▸ | PRKAG2 | Q9UGJ0 | 2/20 | 0.38 |
| ▸ | PRKAB1 | Q9Y478 | 2/20 | 0.38 |
| ▸ | TRPC6 | Q9Y210 | 1/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31343033 | 0.92 | CYP3A4 (0.47) | MAPK7CYP3A4TRPC6TSHRLMNA | |
| SCHEMBL31342876 | 0.90 | CYP3A4 (0.51) | NOS1NOS2MAPK7CYP3A4TRPC6 | |
| SCHEMBL31343053 | 0.87 | CYP3A4 (0.42) | MAPK7CYP3A4TRPC6P2RX7LMNA | |
| SCHEMBL31342909 | 0.85 | TRPC6 (0.41) | NOS1NOS2MAPK7CYP3A4TRPC6 | |
| SCHEMBL31343012 | 0.82 | CYP3A4 (0.43) | CYP3A4TRPC6 | |
| SCHEMBL31343097 | 0.82 | CYP3A4 (0.40) | CYP3A4TRPC6 | |
| SCHEMBL31342842 | 0.82 | CYP3A4 (0.40) | CYP3A4CYP2C9 | |
| SCHEMBL31342995 | 0.82 | CYP3A4 (0.39) | CYP3A4CYP2C9 | |
| SCHEMBL31342829 | 0.81 | GPR119 (0.43) | CYP3A4 | |
| SCHEMBL31342935 | 0.80 | CYP3A4 (0.60) | MAPK7CYP3A4TSHRLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025049495-A1 | TERTIARY PYRIDYL AMINE MODULATORS OF CHOLESTEROL BIOSYNTHESIS AND THEIR USE FOR PROMOTING REMYLINATION | GENENTECH, INC. (US) | 2025-03-06 | — | — | WO | disclosed |