SCHEMBL31343002

SCHEMBL31343002

COc1ccncc1N(c1ccc(S(C)(=O)=O)cc1)C1CCN(C(=O)OC(C)(C)C)CC1

nearest known ligand 0.52

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
GPR119 Q8TDV5 19/20 0.52
NAMPT P43490 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31343093 1.00 GPR119 (0.52) GPR119NAMPT
SCHEMBL31342921 0.88 CYP3A4 (0.52) GPR119
SCHEMBL31342880 0.88 CYP3A4 (0.52) GPR119
SCHEMBL31342885 0.88 MEN1 (0.52) GPR119
SCHEMBL31342991 0.85 GPR119 (0.45) GPR119
SCHEMBL31342829 0.84 GPR119 (0.43) GPR119
SCHEMBL31342989 0.84 GPR119 (0.44) GPR119
SCHEMBL31342997 0.84 GPR119 (0.44) GPR119
SCHEMBL31343009 0.79 CYP3A4 (0.55) GPR119
SCHEMBL31342926 0.79 CYP3A4 (0.42)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025049495-A1 TERTIARY PYRIDYL AMINE MODULATORS OF CHOLESTEROL BIOSYNTHESIS AND THEIR USE FOR PROMOTING REMYLINATION GENENTECH, INC. (US) 2025-03-06 WO disclosed