Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.44 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.43 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.43 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.43 |
| ▸ | OGFRL1 | Q5TC84 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | DPP4 | P27487 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31343835 | 0.86 | SMN1; SMN2 (0.67) | SMN1; SMN2MEN1KMT2AGAACYP1A2 | |
| SCHEMBL31343761 | 0.83 | SMN1; SMN2 (0.59) | SMN1; SMN2MEN1KMT2ACYP1A2CYP2C9 | |
| SCHEMBL7968279 | 0.81 | GAA (0.43) | MEN1KMT2AGAAALDH1A1OPRM1 | |
| SCHEMBL696232 | 0.81 | GAA (0.43) | MEN1KMT2AGAAALDH1A1OPRM1 | |
| SCHEMBL7985048 | 0.81 | GAA (0.43) | MEN1KMT2AGAAALDH1A1OPRM1 | |
| SCHEMBL2102798 | 0.81 | GAA (0.43) | MEN1KMT2AGAAALDH1A1OPRM1 | |
| SCHEMBL31344013 | 0.81 | GAA (0.57) | SMN1; SMN2MEN1KMT2AGAAALDH1A1 | |
| SCHEMBL3436174 | 0.77 | MEN1 (0.54) | SMN1; SMN2MEN1KMT2AGAACYP1A2 | |
| SCHEMBL31013547 | 0.77 | PRKCQ (0.52) | SMN1; SMN2MEN1KMT2ACYP1A2CYP2C9 | |
| SCHEMBL2389846 | 0.74 | MAPT (0.53) | SMN1; SMN2GAAALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240409556-A1 | BENZOPIPERAZINE AND RELATED ANALOGS FOR INHIBITING YAP/TAZ-TEAD | SPRINGWORKS THERAPEUTICS, INC. | 2024-12-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240409556-A1 | BENZOPIPERAZINE AND RELATED ANALOGS FOR INHIBITING YAP/TAZ-TEAD | YAP1, TEAD2, TEAD3 | SMN1; SMN2 2922/4885MEN1 4571/4885KMT2A 2231/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.