SCHEMBL31343643

SCHEMBL31343643

Cc1ccc(S(=O)(=O)Oc2ccc3ccc4ccccc4c3c2)cc1

nearest known ligand 0.60

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 3/20 0.60
TDP1 Q9NUW8 2/20 0.60
HTT P42858 2/20 0.60
LMNA P02545 1/20 0.60
SMN1; SMN2 Q16637 1/20 0.60
MEN1 O00255 2/20 0.58
KMT2A Q03164 2/20 0.58
GAA P10253 2/20 0.56
MAPK1 P28482 1/20 0.56
ENPP2 Q13822 1/20 0.54
TUBB4A P04350 1/20 0.52
TUBB P07437 1/20 0.52
TUBA3C P0DPH7 1/20 0.52
TUBA1B P68363 1/20 0.52
TUBA4A P68366 1/20 0.52
TUBB4B P68371 1/20 0.52
TUBB3 Q13509 1/20 0.52
TUBB2A Q13885 1/20 0.52
TUBB8 Q3ZCM7 1/20 0.52
TUBA3E Q6PEY2 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29930268 0.88 TDP1 (0.78) L3MBTL1TDP1HTTLMNASMN1; SMN2
SCHEMBL6882887 0.88 L3MBTL1 (0.77) L3MBTL1TDP1HTTLMNASMN1; SMN2
SCHEMBL29870275 0.88 L3MBTL1 (0.77) L3MBTL1TDP1HTTLMNASMN1; SMN2
SCHEMBL29930110 0.88 TDP1 (0.58) L3MBTL1TDP1HTTLMNASMN1; SMN2
SCHEMBL29930606 0.88 TDP1 (0.58) L3MBTL1TDP1HTTLMNASMN1; SMN2
SCHEMBL29930612 0.86 L3MBTL1 (0.60) L3MBTL1TDP1HTTLMNASMN1; SMN2
SCHEMBL29930617 0.82 TDP1 (0.52) L3MBTL1TDP1HTTLMNASMN1; SMN2
SCHEMBL22558337 0.81 L3MBTL1 (0.62) L3MBTL1TDP1HTTLMNASMN1; SMN2
SCHEMBL8794066 0.81 MEN1 (0.82) L3MBTL1TDP1HTTLMNASMN1; SMN2
SCHEMBL1305741 0.81 MEN1 (0.54) L3MBTL1TDP1HTTLMNASMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119100962-A Se-deuterated methylation or Se-13Application of C methylation reagent 浙江工业大学 2024-12-10 CN disclosed