SCHEMBL6882887

SCHEMBL6882887

Cc1ccc(S(=O)(=O)Oc2ccc3ccccc3c2)cc1

nearest known ligand 0.77

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 5/20 0.77
HTT P42858 3/20 0.77
TDP1 Q9NUW8 2/20 0.77
LMNA P02545 1/20 0.77
SMN1; SMN2 Q16637 1/20 0.77
MEN1 O00255 2/20 0.73
KMT2A Q03164 2/20 0.73
GAA P10253 1/20 0.70
MAPK1 P28482 1/20 0.70
ENPP2 Q13822 1/20 0.62
CA2 P00918 3/20 0.54
CA1 P00915 1/20 0.54
CA9 Q16790 1/20 0.54
NPSR1 Q6W5P4 2/20 0.51
KEAP1 Q14145 1/20 0.51
NFE2L2 Q16236 1/20 0.51
CA12 O43570 2/20 0.50
ALDH1A1 P00352 2/20 0.50
ESR1 P03372 1/20 0.50
ATM Q13315 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29870275 1.00 L3MBTL1 (0.77) L3MBTL1HTTTDP1LMNASMN1; SMN2
SCHEMBL8794066 0.93 MEN1 (0.82) L3MBTL1HTTTDP1LMNASMN1; SMN2
SCHEMBL22558337 0.90 L3MBTL1 (0.62) L3MBTL1HTTTDP1LMNASMN1; SMN2
Trifluoroacetic Acid SCHEMBL30610914 0.88 MEN1 (0.62) L3MBTL1HTTTDP1LMNASMN1; SMN2
SCHEMBL31343643 0.88 L3MBTL1 (0.60) L3MBTL1HTTTDP1LMNASMN1; SMN2
SCHEMBL26326698 0.87 L3MBTL1 (0.71) L3MBTL1HTTTDP1LMNASMN1; SMN2
SCHEMBL14029074 0.86 TDP1 (0.75) L3MBTL1HTTTDP1LMNASMN1; SMN2
SCHEMBL28296929 0.86 L3MBTL1 (0.75) L3MBTL1HTTTDP1LMNASMN1; SMN2
SCHEMBL2066126 0.85 MEN1 (0.67) L3MBTL1HTTTDP1LMNASMN1; SMN2
SCHEMBL13924688 0.85 MEN1 (0.67) L3MBTL1HTTTDP1LMNASMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 82 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240158424-A1 METHOD FOR PRODUCING DIPHOSPHINE MONOXIDE TAKASAGO INTERNATIONAL CORPORATION (JP) 2024-05-16 US disclosed
EP-4361162-A2 METHOD FOR PRODUCING DIPHOSPHINE MONOXIDE Takasago International Corporation (JP) 2024-05-01 EP disclosed
EP-4310067-A1 METHOD FOR PRODUCING ORGANIC METAL NUCLEOPHILIC AGENT AND REACTION METHOD USING ORGANIC METAL NUCLEOPHILIC AGENT National University Corporation Hokkaido University (JP) 2024-01-24 EP disclosed
CN-117324042-A Catalytic system for deoxidizing phenolic derivative, and mild and efficient deoxidizing method and application thereof 中国科学院长春应用化学研究所 2024-01-02 CN disclosed
CN-117024312-A Aryl sulfonyl fluoride and preparation method using aryl sulfonium salt as substrate 上海应用技术大学 2023-11-10 CN disclosed
US-20230271988-A1 METHOD FOR PRODUCING ORGANOMETALLIC NUCLEOPHILE AND REACTION METHOD USING ORGANOMETALLIC NUCLEOPHILE NATIONAL UNIVERSITY CORPORATION HOKKAIDO UNIVERSITY (JP) 2023-08-31 US disclosed
US-20230271988-A1 METHOD FOR PRODUCING ORGANOMETALLIC NUCLEOPHILE AND REACTION METHOD USING ORGANOMETALLIC NUCLEOPHILE NATIONAL UNIVERSITY CORPORATION HOKKAIDO UNIVERSITY (JP) 2023-08-31 US disclosed
WO-2022196796-A1 METHOD FOR PRODUCING ORGANIC METAL NUCLEOPHILIC AGENT AND REACTION METHOD USING ORGANIC METAL NUCLEOPHILIC AGENT 国立大学法人北海道大学 2022-09-22 WO disclosed
US-10463391-B2 Magnetic ferrocenyl-functionalized nanoparticle KING FAHD UNIVERSITY OF PETROLEUM AND MINERALS (SA) 2019-11-05 US disclosed
US-10370397-B2 Phosphine substituted ferrocenyl complex Kind Fahd University of Petroleum and Minerals (SA) 2019-08-06 US disclosed
US-20040260039-A1 Process for producing organic compound epoxy resin composition, cured article obtained from the epoxy resin, and semiconductor device obtained with epoxy resin MITSUI CHEMICALS, INC. (JP) 2004-12-23 US disclosed
EP-1167372-B1 2,2-(Diaryl)vinylphosphine compound, palladium catalyst thereof, and process for producing arylamine, diaryl, or arylalkyne with the catalyst TAKASAGO PERFUMERY CO LTD (JP) 2003-12-10 EP disclosed
EP-0950649-B1 A process for preparing oxyalkylene derivatives in the presence of phosphine oxides MITSUI CHEMICALS INC (JP) 2003-03-26 EP disclosed
US-6455720-B1 AS CATALYSTS TAKASAGO INTERNATIONAL CORPORATION (JP) 2002-09-24 US disclosed
US-20020058837-A1 2,2 (Diarlyl) Vinylphosphine compound, palladium catalyst thereof, and process for producing arylamine, diaryl, or arylalkyne with the catalyst TAKASAGO INTERNATIONAL CORPORATION (JP) 2002-05-16 US disclosed
US-6365776-B1 FROM ORGANOHALOGEN COMPOUND AND AMINE USING PALLADIUM COMPOUND CATALYST AND PROMOTER TAKASAGO INTERNATIONAL CORPORATION (JP) 2002-04-02 US disclosed
US-20020035295-A1 PROCESS FOR PRODUCING AROMATIC AMINES TAKASAGO INTERNATIONAL CORPORATION 2002-03-21 US disclosed
EP-1167372-A1 2,2-(Diaryl)vinylphosphine compound, palladium catalyst thereof, and process for producing arylamine, diaryl, or arylalkyne with the catalyst Takasago International Corporation (JP) 2002-01-02 EP disclosed
US-6130346-A ESTERIFICATION, CARBONATION, SULFONATION, ETHERIFICATION MITSUI CHEMICALS, INC. (JP) 2000-10-10 US disclosed
EP-0950649-A1 A process for preparing oxyalkylene derivatives in the presence of phosphine oxides Mitsui Chemicals, Inc. (JP) 1999-10-20 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240158424-A1 METHOD FOR PRODUCING DIPHOSPHINE MONOXIDE TDO2, SCO2, DUOX1 L3MBTL1 3112/4885HTT 4518/4885TDP1 1033/4885
US-20020035295-A1 PROCESS FOR PRODUCING AROMATIC AMINES TYR, DDC, PNMT L3MBTL1 3745/4885HTT 827/4885TDP1 3847/4885
US-20020058837-A1 2,2 (Diarlyl) Vinylphosphine compound, palladium catalyst thereof, and process for producing arylamine, diaryl, or arylalkyne with the catalyst DDT, PDCD11, PLD2 L3MBTL1 1659/4885HTT 2220/4885TDP1 3460/4885
US-20230271988-A1 METHOD FOR PRODUCING ORGANOMETALLIC NUCLEOPHILE AND REACTION METHOD USING ORGANOMETALLIC NUCLEOPHILE HPD, TALDO1, OGG1 L3MBTL1 2878/4885HTT 3473/4885TDP1 2696/4885
US-10370397-B2 Phosphine substituted ferrocenyl complex FECH, PHOSPHO1, FTH1 L3MBTL1 2275/4885HTT 3477/4885TDP1 4869/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.