Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Salicylic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNB2 | P17787 | 1/20 | 0.45 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.45 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.45 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.45 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.45 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.44 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | BLM | P54132 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Salicylic Acid SCHEMBL27199926 | 1.00 | CHRNB2 (0.45) | CHRNB2CHRNB4CHRNA3CHRNA7CHRNA4 | |
| Benzoic Acid SCHEMBL31344206 | 0.87 | CHRNB2 (0.49) | CHRNB2CHRNB4CHRNA3CHRNA7CHRNA4 | |
| Benzoic Acid SCHEMBL27199904 | 0.87 | CHRNB2 (0.49) | CHRNB2CHRNB4CHRNA3CHRNA7CHRNA4 | |
| Acetic Acid SCHEMBL27199884 | 0.84 | KDM4E (0.45) | KDM4EBLMALOX15 | |
| Acetic Acid SCHEMBL31344147 | 0.84 | KDM4E (0.45) | KDM4EBLMALOX15 | |
| Salicylic Acid SCHEMBL31344154 | 0.84 | AADAT (0.42) | CHRNB2CHRNB4CHRNA3CHRNA7CHRNA4 | |
| Salicylic Acid SCHEMBL27199836 | 0.84 | AADAT (0.42) | CHRNB2CHRNB4CHRNA3CHRNA7CHRNA4 | |
| SCHEMBL11237611 | 0.81 | CHRNA1 (0.51) | CHRNB2CHRNB4CHRNA3CHRNA4 | |
| SCHEMBL30866541 | 0.81 | CHRNA1 (0.51) | CHRNB2CHRNB4CHRNA3CHRNA4 | |
| SCHEMBL27199892 | 0.81 | CHRNA1 (0.51) | CHRNB2CHRNB4CHRNA3CHRNA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118984653-A | Vaporizable alkaloid compositions and methods of use thereof | 瑞迪美天然有限公司 | 2024-11-19 | — | — | CN | disclosed |