Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 1/20 | 0.40 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.36 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.36 |
| ▸ | ASGR1 | P07306 | 1/20 | 0.36 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.34 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.34 |
| ▸ | RELA | Q04206 | 1/20 | 0.34 |
| ▸ | SPR | P35270 | 6/20 | 0.34 |
| ▸ | KDM4D | Q6B0I6 | 1/20 | 0.34 |
| ▸ | BUB1 | O43683 | 1/20 | 0.34 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.32 |
| ▸ | MT-CO2 | P00403 | 1/20 | 0.32 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.32 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.31 |
| ▸ | THRB | P10828 | 1/20 | 0.31 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25512753 | 1.00 | HSD11B1 (0.40) | HSD11B1DDB1CRBNASGR1NFKB1 | |
| SCHEMBL5370355 | 1.00 | HSD11B1 (0.40) | HSD11B1DDB1CRBNASGR1NFKB1 | |
| SCHEMBL132240 | 0.92 | HSD11B1 (0.41) | HSD11B1DDB1CRBNASGR1NFKB1 | |
| SCHEMBL31071193 | 0.90 | HSD11B1 (0.39) | HSD11B1DDB1CRBNASGR1NFKB1 | |
| SCHEMBL24874898 | 0.89 | HSD11B1 (0.38) | HSD11B1DDB1CRBNASGR1NFKB1 | |
| SCHEMBL21274075 | 0.86 | HSD11B1 (0.41) | HSD11B1DDB1CRBNASGR1NFKB1 | |
| SCHEMBL24137969 | 0.86 | HSD11B1 (0.38) | HSD11B1DDB1CRBNASGR1NFKB1 | |
| SCHEMBL14239667 | 0.80 | HSD11B1 (0.40) | HSD11B1DDB1CRBNASGR1NFKB1 | |
| SCHEMBL190837 | 0.80 | HSD11B1 (0.47) | HSD11B1DDB1CRBNASGR1NFKB1 | |
| SCHEMBL24969074 | 0.79 | NFKB1 (0.41) | HSD11B1DDB1CRBNNFKB1NFKB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118984829-A | BTK inhibitors | 渤健马萨诸塞州股份有限公司 | 2024-11-19 | — | — | CN | disclosed |