Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALK | Q9UM73 | 8/20 | 0.54 |
| ▸ | INSR | P06213 | 6/20 | 0.54 |
| ▸ | IGF1R | P08069 | 6/20 | 0.54 |
| ▸ | MAP4K1 | Q92918 | 7/20 | 0.50 |
| ▸ | ULK1 | O75385 | 1/20 | 0.49 |
| ▸ | CDK7 | P50613 | 1/20 | 0.46 |
| ▸ | CDK9 | P50750 | 1/20 | 0.46 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.46 |
| ▸ | LRRK2 | Q5S007 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31229842 | 0.91 | ALK (0.62) | ALKINSRIGF1RMAP4K1CDK7 | |
| SCHEMBL26717249 | 0.78 | INSR (0.72) | ALKINSRIGF1RMAP4K1CDK7 | |
| SCHEMBL30725504 | 0.77 | BCL6 (0.53) | ALKINSRIGF1RMAP4K1ULK1 | |
| SCHEMBL28969605 | 0.77 | AURKA (0.69) | PTK2 | |
| SCHEMBL24752248 | 0.76 | PTK2 (0.60) | ULK1PTK2 | |
| SCHEMBL24752259 | 0.75 | PTK2 (0.59) | ALKPTK2 | |
| SCHEMBL21557830 | 0.74 | ALK (0.81) | ALKINSRIGF1RMAP4K1PTK2 | |
| SCHEMBL29832975 | 0.74 | MAP4K1 (0.56) | ALKINSRIGF1RMAP4K1PTK2 | |
| SCHEMBL29832994 | 0.72 | ALK (0.47) | ALKINSRIGF1RMAP4K1ULK1 | |
| SCHEMBL29833039 | 0.72 | ALK (0.50) | ALKINSRIGF1RMAP4K1CDK7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024240118-A1 | PREPARATION FOR AND USE OF HETEROARYL DERIVATIVES | 广州智睿医药科技有限公司 | 2024-11-28 | — | — | WO | claimed |
| WO-2024240118-A1 | PREPARATION FOR AND USE OF HETEROARYL DERIVATIVES | 广州智睿医药科技有限公司 | 2024-11-28 | — | — | WO | disclosed |