Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCL6 | P41182 | 1/20 | 0.53 |
| ▸ | ALK | Q9UM73 | 7/20 | 0.49 |
| ▸ | INSR | P06213 | 6/20 | 0.49 |
| ▸ | IGF1R | P08069 | 6/20 | 0.49 |
| ▸ | CDK7 | P50613 | 1/20 | 0.48 |
| ▸ | CDK9 | P50750 | 1/20 | 0.48 |
| ▸ | MAP4K1 | Q92918 | 8/20 | 0.46 |
| ▸ | ULK1 | O75385 | 1/20 | 0.44 |
| ▸ | MAPK10 | P53779 | 2/20 | 0.43 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.43 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29833125 | 0.90 | BCL6 (0.48) | BCL6ALKINSRIGF1RCDK7 | |
| SCHEMBL13832208 | 0.87 | CDK7 (0.61) | BCL6ALKINSRIGF1RCDK7 | |
| SCHEMBL29833319 | 0.87 | CDK7 (0.61) | BCL6ALKINSRIGF1RCDK7 | |
| SCHEMBL31344564 | 0.77 | ALK (0.54) | ALKINSRIGF1RCDK7CDK9 | |
| SCHEMBL24752259 | 0.77 | PTK2 (0.59) | ALKMAPK10MAPK9 | |
| SCHEMBL28969605 | 0.76 | AURKA (0.69) | MAPK10MAPK9 | |
| SCHEMBL24752248 | 0.75 | PTK2 (0.60) | ULK1MAPK10MAPK8MAPK9 | |
| SCHEMBL30500640 | 0.75 | ULK1 (0.74) | BCL6ALKINSRIGF1RCDK7 | |
| SCHEMBL30001749 | 0.74 | PTK2 (0.45) | ALKINSRIGF1RCDK7CDK9 | |
| SCHEMBL28969589 | 0.74 | PTK2 (0.45) | ALKINSRIGF1RCDK7CDK9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117430589-A | 2-aminopyrimidine compound or salt thereof, and preparation method and application thereof | 励缔(杭州)医药科技有限公司 | 2024-01-23 | — | — | CN | disclosed |