SCHEMBL31344697

SCHEMBL31344697

CCSc1cc(Cl)cnc1C(N)=NO

nearest known ligand 0.40

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
NPSR1 Q6W5P4 2/20 0.40
PLAU P00749 5/20 0.34
NOS3 P29474 2/20 0.33
NOS1 P29475 2/20 0.33
NOS2 P35228 2/20 0.33
AOC3 Q16853 1/20 0.32
MAPT P10636 2/20 0.31
ALDH1A1 P00352 1/20 0.31
LMNA P02545 1/20 0.31
HPGD P15428 1/20 0.31
XBP1 P17861 1/20 0.31
ADRA2A P08913 1/20 0.30
ADRA2B P18089 1/20 0.30
ADRA2C P18825 1/20 0.30
FLT3 P36888 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29257091 0.82 NPSR1 (0.40) NPSR1PLAUAOC3MAPT
SCHEMBL31344690 0.79 NPSR1 (0.35) NPSR1PLAU
SCHEMBL17732167 0.77 MAPT (0.37) MAPTALDH1A1LMNAHPGD
SCHEMBL30177536 0.77 MAPT (0.37) MAPTALDH1A1LMNAHPGD
SCHEMBL23413780 0.77 EGLN1 (0.39) MAPTALDH1A1LMNAHPGD
SCHEMBL24973039 0.75 MAPT (0.34) PLAUAOC3MAPTALDH1A1HPGD
SCHEMBL4586975 0.74 PLAU (0.40) NPSR1PLAUMAPTALDH1A1LMNA
SCHEMBL31344739 0.74 PLAU (0.36) PLAUALDH1A1
SCHEMBL23413547 0.72 ALDH1A1 (0.44) NPSR1MAPTALDH1A1HPGDXBP1
SCHEMBL30191386 0.72 ALOX15 (0.41) MAPTALDH1A1LMNAHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4724447-A1 SYNTHESIS OF CYCLIC ACYL SULFOXIMINES Syngenta Crop Protection AG (CH) 2026-04-15 EP disclosed
WO-2024252006-A1 SYNTHESIS OF CYCLIC ACYL SULFOXIMINES SYNGENTA CROP PROTECTION AG (CH) 2024-12-12 WO disclosed