Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.32 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.32 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.31 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31344809 | 0.76 | SMN1; SMN2 (0.38) | SMN1; SMN2ALDH1A1MAPTNPC1TP53 | |
| SCHEMBL31344826 | 0.72 | PKMYT1 (0.34) | SMN1; SMN2KDM4E | |
| SCHEMBL27403357 | 0.72 | MAPT (0.39) | ALDH1A1MAPTHSD17B10GAAKDM4E | |
| SCHEMBL31344829 | 0.70 | GPR35 (0.35) | ALDH1A1HSD17B10GAAKDM4E | |
| SCHEMBL31344823 | 0.68 | SMN1; SMN2 (0.46) | SMN1; SMN2ALDH1A1MAPTNPC1TP53 | |
| SCHEMBL27403571 | 0.67 | KDM4E (0.36) | SMN1; SMN2ALDH1A1MAPTNPC1TP53 | |
| SCHEMBL25156246 | 0.66 | PSMB8 (0.44) | SMN1; SMN2ALDH1A1MAPTNPC1TP53 | |
| SCHEMBL25604313 | 0.64 | SMN1; SMN2 (0.53) | SMN1; SMN2ALDH1A1MAPTNPC1TP53 | |
| SCHEMBL25604312 | 0.64 | SMN1; SMN2 (0.53) | SMN1; SMN2ALDH1A1MAPTNPC1TP53 | |
| SCHEMBL30971303 | 0.63 | CSNK2A1 (0.33) | ALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119569651-A | Carboxamide derivatives, pharmaceutical compositions containing the same, and preparation method and application thereof | 四川科伦博泰生物医药股份有限公司 | 2025-03-07 | — | — | CN | disclosed |