Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.33 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31344827 | 0.76 | SMN1; SMN2 (0.35) | SMN1; SMN2NPC1RAB9AALDH1A1TP53 | |
| SCHEMBL17115155 | 0.74 | SMN1; SMN2 (0.39) | SMN1; SMN2NPC1RAB9AALDH1A1TP53 | |
| SCHEMBL16518738 | 0.73 | SMN1; SMN2 (0.42) | SMN1; SMN2NPC1RAB9AALDH1A1TP53 | |
| SCHEMBL31344823 | 0.72 | SMN1; SMN2 (0.46) | SMN1; SMN2NPC1RAB9AALDH1A1TP53 | |
| SCHEMBL31500704 | 0.70 | TLR8 (0.36) | SMN1; SMN2NPC1RAB9AHSD17B10TLR8 | |
| SCHEMBL17115195 | 0.67 | SMN1; SMN2 (0.39) | SMN1; SMN2NPC1RAB9AALDH1A1TP53 | |
| SCHEMBL24401989 | 0.66 | SMN1; SMN2 (0.42) | SMN1; SMN2NPC1RAB9AALDH1A1TP53 | |
| SCHEMBL16437413 | 0.66 | SMN1; SMN2 (0.43) | SMN1; SMN2NPC1RAB9AALDH1A1TP53 | |
| SCHEMBL17115183 | 0.66 | GAA (0.44) | SMN1; SMN2NPC1RAB9AALDH1A1TP53 | |
| SCHEMBL19884338 | 0.65 | NPC1 (0.34) | SMN1; SMN2NPC1RAB9AALDH1A1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119569651-A | Carboxamide derivatives, pharmaceutical compositions containing the same, and preparation method and application thereof | 四川科伦博泰生物医药股份有限公司 | 2025-03-07 | — | — | CN | disclosed |