SCHEMBL31346101

SCHEMBL31346101

Cc1cc2c(cc1F)CC(c1cccc(Br)c1)O2

nearest known ligand 0.40

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
FFAR1 O14842 5/20 0.38
KDM1A O60341 2/20 0.35
MAOB P27338 10/20 0.34
HTR2A P28223 1/20 0.34
HTR2C P28335 1/20 0.34
HTR2B P41595 1/20 0.34
HRH3 Q9Y5N1 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31346125 0.89 KDM1A (0.38) FFAR1KDM1AMAOBHTR2AHTR2C
SCHEMBL31346190 0.84 FFAR1 (0.35) FFAR1KDM1AMAOB
SCHEMBL31346096 0.84 FFAR1 (0.40) FFAR1KDM1AMAOBHTR2AHTR2C
SCHEMBL31346103 0.82 FFAR1 (0.35) FFAR1KDM1AMAOB
SCHEMBL31346053 0.81 CYP19A1 (0.42) FFAR1
SCHEMBL31345958 0.78 KDM1A (0.38) FFAR1KDM1AHTR2AHTR2CHTR2B
SCHEMBL31346011 0.74 FFAR1 (0.36) FFAR1KDM1AMAOB
SCHEMBL31346002 0.74 TEAD1 (0.42) FFAR1KDM1AHTR2CHTR2B
SCHEMBL31345963 0.74 TEAD1 (0.42) FFAR1KDM1AHTR2CHTR2B
SCHEMBL31346113 0.71 KDM1A (0.35) FFAR1KDM1AHTR2AHTR2CHTR2B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4712967-A2 G-PROTEIN COUPLED RECEPTOR ANTAGONIST Enveda Therapeutics, Inc. (US) 2026-03-25 EP disclosed
WO-2024239000-A2 G-PROTEIN COUPLED RECEPTOR ANTAGONIST ENVEDA THERAPEUTICS, INC. (US) 2024-11-21 WO disclosed