SCHEMBL31346103

SCHEMBL31346103

Fc1cc2c(cc1Cl)CC(c1cccc(Br)c1)O2

nearest known ligand 0.38

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
FFAR1 O14842 4/20 0.35
TRPM5 Q9NZQ8 1/20 0.35
KDM1A O60341 2/20 0.35
MAOB P27338 3/20 0.34
SIRT2 Q8IXJ6 1/20 0.34
TTR P02766 1/20 0.33
CYP19A1 P11511 1/20 0.33
KMT2A Q03164 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31346190 0.95 FFAR1 (0.35) FFAR1TRPM5KDM1AMAOBSIRT2
SCHEMBL31345958 0.89 KDM1A (0.38) FFAR1KDM1ATTRCYP19A1
SCHEMBL31346125 0.89 KDM1A (0.38) FFAR1KDM1AMAOBCYP19A1KMT2A
SCHEMBL31346063 0.86 TTR (0.32) FFAR1TRPM5TTR
SCHEMBL31346096 0.84 FFAR1 (0.40) FFAR1KDM1AMAOBSIRT2KMT2A
SCHEMBL31346046 0.83 FFAR1 (0.38) FFAR1MAOB
SCHEMBL31346101 0.82 FFAR1 (0.38) FFAR1KDM1AMAOB
SCHEMBL31346143 0.81 LDHA (0.46) TRPM5SIRT2CYP19A1
SCHEMBL31345983 0.80 ALDH1A1 (0.45) FFAR1TRPM5MAOBTTRCYP19A1
SCHEMBL31346122 0.78 AHR (0.33) TRPM5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4712967-A2 G-PROTEIN COUPLED RECEPTOR ANTAGONIST Enveda Therapeutics, Inc. (US) 2026-03-25 EP disclosed
WO-2024239000-A2 G-PROTEIN COUPLED RECEPTOR ANTAGONIST ENVEDA THERAPEUTICS, INC. (US) 2024-11-21 WO disclosed