Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CFTR | P13569 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.43 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.42 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.41 |
| ▸ | MRGPRX4 | Q96LA9 | 4/20 | 0.40 |
| ▸ | KMO | O15229 | 1/20 | 0.40 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.40 |
| ▸ | AKR1C2 | P52895 | 2/20 | 0.40 |
| ▸ | PTGER4 | P35408 | 2/20 | 0.39 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.39 |
| ▸ | CES2 | O00748 | 1/20 | 0.38 |
| ▸ | CCR2 | P41597 | 1/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
| ▸ | ERAP1 | Q9NZ08 | 1/20 | 0.38 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.38 |
| ▸ | AKR1C4 | P17516 | 1/20 | 0.38 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.38 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.38 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31346099 | 0.91 | CFTR (0.49) | CFTRALDH1A1FFAR1SRD5A2PTGDR2 | |
| SCHEMBL31345978 | 0.91 | CFTR (0.49) | CFTRALDH1A1FFAR1SRD5A2PTGDR2 | |
| SCHEMBL31345959 | 0.80 | PARP1 (0.51) | CFTRFFAR1MRGPRX4CES2 | |
| SCHEMBL31346108 | 0.80 | CFTR (0.49) | CFTRFFAR1SRD5A2PTGDR2MRGPRX4 | |
| SCHEMBL31346170 | 0.80 | CFTR (0.49) | CFTRFFAR1SRD5A2PTGDR2MRGPRX4 | |
| SCHEMBL31346052 | 0.79 | TDP1 (0.47) | CFTRALDH1A1FFAR1MRGPRX4KMO | |
| SCHEMBL31346090 | 0.78 | ALDH1A1 (0.43) | CFTRALDH1A1FFAR1SRD5A2PTGDR2 | |
| SCHEMBL31346025 | 0.78 | HDAC8 (0.45) | CFTRFFAR1 | |
| SCHEMBL31346154 | 0.78 | ALDH1A1 (0.49) | ALDH1A1FFAR1MRGPRX4KMO | |
| SCHEMBL31346021 | 0.77 | CYP19A1 (0.42) | FFAR1PTGDR2MRGPRX4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4712967-A2 | G-PROTEIN COUPLED RECEPTOR ANTAGONIST | Enveda Therapeutics, Inc. (US) | 2026-03-25 | — | — | EP | disclosed |
| WO-2024239000-A2 | G-PROTEIN COUPLED RECEPTOR ANTAGONIST | ENVEDA THERAPEUTICS, INC. (US) | 2024-11-21 | — | — | WO | disclosed |