Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 4/20 | 0.45 |
| ▸ | JAK2 | O60674 | 1/20 | 0.41 |
| ▸ | JAK1 | P23458 | 1/20 | 0.41 |
| ▸ | PPARA | Q07869 | 1/20 | 0.40 |
| ▸ | YAP1 | P46937 | 3/20 | 0.40 |
| ▸ | STS | P08842 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | KLK7 | P49862 | 1/20 | 0.39 |
| ▸ | KLK5 | Q9Y337 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31346209 | 1.00 | GPR119 (0.45) | GPR119JAK2JAK1PPARAYAP1 | |
| SCHEMBL22764724 | 0.99 | GPR119 (0.46) | GPR119JAK2JAK1PPARAYAP1 | |
| SCHEMBL28709765 | 0.99 | GPR119 (0.46) | GPR119JAK2JAK1PPARAYAP1 | |
| SCHEMBL25957354 | 0.96 | GPR119 (0.42) | GPR119JAK2JAK1PPARAYAP1 | |
| SCHEMBL30543960 | 0.94 | GPR119 (0.41) | GPR119JAK2JAK1PPARAYAP1 | |
| SCHEMBL25959422 | 0.94 | GPR119 (0.41) | GPR119JAK2JAK1PPARAYAP1 | |
| SCHEMBL23761168 | 0.91 | PPARA (0.42) | GPR119JAK2JAK1PPARAYAP1 | |
| SCHEMBL31291041 | 0.91 | PPARA (0.42) | GPR119JAK2JAK1PPARAYAP1 | |
| SCHEMBL28709758 | 0.91 | PPARA (0.42) | GPR119JAK2JAK1PPARAYAP1 | |
| SCHEMBL23761169 | 0.91 | PPARA (0.42) | GPR119JAK2JAK1PPARAYAP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4746968-A1 | PYRROLIDINE COMPOUNDS LP(A) LOWERING ACTIVITY | Eli Lilly and Company (US) | 2026-05-27 | — | — | EP | disclosed |
| WO-2025024216-A1 | PYRROLIDINE COMPOUNDS Lp(a) LOWERING ACTIVITY | ELI LILLY AND COMPANY (US) | 2025-01-30 | — | — | WO | disclosed |