Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BMX | P51813 | 2/20 | 0.58 |
| ▸ | FLT3 | P36888 | 7/20 | 0.55 |
| ▸ | KLK7 | P49862 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 4/20 | 0.42 |
| ▸ | RAB9A | P51151 | 4/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | ACP1 | P24666 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31346225 | 0.85 | FLT3 (0.61) | BMXFLT3NPC1RAB9AKDM4E | |
| SCHEMBL12439616 | 0.74 | BMX (0.53) | BMXFLT3NPC1RAB9AKDM4E | |
| SCHEMBL12403847 | 0.69 | FLT3 (0.52) | BMXFLT3NPC1RAB9AKDM4E | |
| SCHEMBL12439612 | 0.68 | FLT3 (0.47) | BMXFLT3NPC1RAB9AKDM4E | |
| SCHEMBL2816214 | 0.67 | ADORA2A (0.63) | NPC1RAB9AKDM4EALDH1A1LMNA | |
| SCHEMBL31346262 | 0.67 | KDM4E (0.45) | BMXNPC1RAB9AKDM4EALDH1A1 | |
| SCHEMBL2816389 | 0.66 | HTR2C (0.47) | BMXNPC1RAB9AKDM4EALDH1A1 | |
| SCHEMBL18033282 | 0.66 | FLT3 (0.54) | BMXFLT3NPC1RAB9AKDM4E | |
| SCHEMBL4677894 | 0.65 | MAPT (0.58) | NPC1RAB9AKDM4ELMNAPOLB | |
| SCHEMBL12403848 | 0.65 | ALDH1A1 (0.56) | FLT3NPC1RAB9AALDH1A1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114423763-B | Regioselective synthesis of imidazo [1,2-a ] pyrimidines | 豪夫迈·罗氏有限公司 | 2025-01-21 | — | — | CN | disclosed |