Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.45 |
| ▸ | MEN1 | O00255 | 4/20 | 0.45 |
| ▸ | RAB9A | P51151 | 4/20 | 0.45 |
| ▸ | NPC1 | O15118 | 3/20 | 0.45 |
| ▸ | LMNA | P02545 | 3/20 | 0.45 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.44 |
| ▸ | TOP2A | P11388 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.41 |
| ▸ | BMX | P51813 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | GALR3 | O60755 | 1/20 | 0.37 |
| ▸ | NR2F2 | P24468 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31346258 | 0.85 | ADORA2A (0.48) | KDM4EKMT2AMEN1RAB9ANPC1 | |
| SCHEMBL2816214 | 0.74 | ADORA2A (0.63) | KDM4EKMT2AMEN1RAB9ANPC1 | |
| SCHEMBL29892566 | 0.71 | ADORA2A (0.49) | KDM4EKMT2AMEN1RAB9ANPC1 | |
| SCHEMBL31346231 | 0.67 | BMX (0.58) | KDM4EKMT2AMEN1RAB9ANPC1 | |
| SCHEMBL31346253 | 0.66 | SMN1; SMN2 (0.52) | KDM4EKMT2AMEN1RAB9ANPC1 | |
| SCHEMBL2816389 | 0.66 | HTR2C (0.47) | KDM4EKMT2AMEN1RAB9ANPC1 | |
| SCHEMBL11823273 | 0.65 | ALDH1A1 (0.50) | KDM4EKMT2AMEN1LMNAADORA2A | |
| SCHEMBL31346257 | 0.65 | TNKS (0.53) | KDM4EKMT2ARAB9ANPC1POLB | |
| SCHEMBL2818071 | 0.64 | GAA (0.48) | KDM4ELMNAADORA2ATOP2AALDH1A1 | |
| SCHEMBL11738659 | 0.64 | KMT2A (0.51) | KDM4EKMT2AMEN1RAB9ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114423763-B | Regioselective synthesis of imidazo [1,2-a ] pyrimidines | 豪夫迈·罗氏有限公司 | 2025-01-21 | — | — | CN | disclosed |