Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STIM1 | Q13586 | 2/20 | 0.54 |
| ▸ | ORAI1 | Q96D31 | 2/20 | 0.54 |
| ▸ | PTGS2 | P35354 | 6/20 | 0.44 |
| ▸ | PTGS1 | P23219 | 4/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | USP1 | O94782 | 5/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | THPO | P40225 | 1/20 | 0.40 |
| ▸ | BLM | P54132 | 1/20 | 0.40 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.40 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25200602 | 0.84 | STIM1 (0.58) | STIM1ORAI1PTGS2PTGS1MAPT | |
| SCHEMBL14226059 | 0.82 | STIM1 (0.54) | STIM1ORAI1PTGS2PTGS1MAPT | |
| SCHEMBL25184772 | 0.82 | STIM1 (0.54) | STIM1ORAI1PTGS2PTGS1MAPT | |
| SCHEMBL14240853 | 0.79 | STIM1 (0.51) | STIM1ORAI1PTGS2PTGS1MAPT | |
| SCHEMBL25180836 | 0.79 | STIM1 (0.54) | STIM1ORAI1PTGS2PTGS1MAPT | |
| SCHEMBL30443166 | 0.79 | STIM1 (0.54) | STIM1ORAI1PTGS2PTGS1MAPT | |
| SCHEMBL25465526 | 0.79 | STIM1 (0.51) | STIM1ORAI1PTGS2PTGS1MAPT | |
| SCHEMBL25466518 | 0.78 | PTGS2 (0.56) | STIM1ORAI1PTGS2PTGS1MAPT | |
| SCHEMBL25711937 | 0.78 | PTGS1 (0.41) | STIM1ORAI1PTGS2PTGS1 | |
| SCHEMBL25203381 | 0.78 | USP1 (0.42) | STIM1ORAI1PTGS2PTGS1USP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4713319-A1 | SMALL MOLECULE INHIBITORS OF UBIQUITIN SPECIFIC PROTEASE 1 (USP1) AND USES THEREOF | Insilico Medicine IP Limited (HK) | 2026-03-25 | — | — | EP | disclosed |
| WO-2024236528-A1 | SMALL MOLECULE INHIBITORS OF UBIQUITIN SPECIFIC PROTEASE 1 (USP1) AND USES THEREOF | INSILICO MEDICINE IP LIMITED (CN) | 2024-11-21 | — | — | WO | disclosed |