Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DYRK1A | Q13627 | 1/20 | 0.39 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.37 |
| ▸ | FLT3 | P36888 | 1/20 | 0.37 |
| ▸ | PLK3 | Q9H4B4 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | JAK2 | O60674 | 3/20 | 0.33 |
| ▸ | PDPK1 | O15530 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26108747 | 1.00 | DYRK1A (0.39) | DYRK1ACHEK1FLT3PLK3MAPT | |
| SCHEMBL25239396 | 0.79 | — | — | |
| SCHEMBL26104190 | 0.72 | MAPT (0.38) | MAPTCYP1A2CYP3A4CYP2D6MAPK1 | |
| SCHEMBL30612183 | 0.72 | MAPT (0.38) | MAPTCYP1A2CYP3A4CYP2D6MAPK1 | |
| SCHEMBL10565223 | 0.68 | CHEK1 (0.41) | CHEK1FLT3PLK3MAPTGAA | |
| SCHEMBL26107697 | 0.67 | ALPL (0.40) | MAPTTP53CYP1A2CYP3A4CYP2C9 | |
| SCHEMBL22715904 | 0.66 | ADORA2A (0.39) | — | |
| SCHEMBL29439732 | 0.66 | ADORA2A (0.39) | — | |
| SCHEMBL19994996 | 0.64 | JAK2 (0.47) | DYRK1ACHEK1FLT3PLK3MAPT | |
| SCHEMBL29498562 | 0.64 | JAK2 (0.47) | DYRK1ACHEK1FLT3PLK3MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119585252-A | Bicyclic heteroaryl containing compounds as IKZF2 degrading agents | 翁科皮亚治疗公司和SK生命科学实验室 | 2025-03-07 | — | — | CN | disclosed |