Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
| ▸ | PLA2G2A | P14555 | 4/20 | 0.42 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.41 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | DHODH | Q02127 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | ADCY10 | Q96PN6 | 1/20 | 0.38 |
| ▸ | CNR1 | P21554 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26108698 | 1.00 | KDM4E (0.50) | KDM4EPLA2G2ATLR8TLR7ALDH1A1 | |
| SCHEMBL31347211 | 0.86 | KDM4E (0.57) | KDM4EPLA2G2AALDH1A1GAAMAPT | |
| SCHEMBL26107749 | 0.86 | KDM4E (0.57) | KDM4EPLA2G2AALDH1A1GAAMAPT | |
| SCHEMBL26108715 | 0.80 | MCL1 (0.35) | KDM4EALDH1A1MAPTPOLBDHODH | |
| SCHEMBL26107392 | 0.79 | LTA4H (0.36) | — | |
| SCHEMBL26107710 | 0.79 | KDM4E (0.52) | KDM4EPLA2G2AALDH1A1GAAMAPT | |
| SCHEMBL30611894 | 0.79 | KDM4E (0.52) | KDM4EPLA2G2AALDH1A1GAAMAPT | |
| SCHEMBL30612045 | 0.78 | KDM4E (0.46) | KDM4EPLA2G2AALDH1A1GAAMAPT | |
| SCHEMBL26108500 | 0.78 | KDM4E (0.46) | KDM4EPLA2G2AALDH1A1GAAMAPT | |
| SCHEMBL4348470 | 0.76 | TSHR (0.52) | KDM4EALDH1A1GAAMAPTPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119585252-A | Bicyclic heteroaryl containing compounds as IKZF2 degrading agents | 翁科皮亚治疗公司和SK生命科学实验室 | 2025-03-07 | — | — | CN | disclosed |