Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 1/20 | 0.40 |
| ▸ | PPARG | P37231 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.36 |
| ▸ | MEN1 | O00255 | 3/20 | 0.36 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | JAK1 | P23458 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | GFER | P55789 | 1/20 | 0.35 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.34 |
| ▸ | GPR27 | Q9NS67 | 2/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | MEP1B | Q16820 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19994876 | 0.78 | KMT2A (0.51) | IDO1KMT2AMEN1TDP1ALDH1A1 | |
| SCHEMBL29498627 | 0.78 | KMT2A (0.51) | IDO1KMT2AMEN1TDP1ALDH1A1 | |
| SCHEMBL20692331 | 0.77 | SOS1 (0.37) | KMT2AMEN1PABPC1GFER | |
| SCHEMBL3017872 | 0.76 | LMNA (0.49) | IDO1KMT2AMEN1TDP1ALDH1A1 | |
| SCHEMBL25387423 | 0.76 | EDNRB (0.50) | KMT2AMEN1TDP1ALDH1A1LMNA | |
| SCHEMBL30562770 | 0.76 | EDNRB (0.50) | KMT2AMEN1TDP1ALDH1A1LMNA | |
| SCHEMBL22013636 | 0.75 | NMT1 (0.52) | PPARGKMT2AJAK1CYP3A4CYP2C9 | |
| SCHEMBL29130981 | 0.73 | CA1 (0.47) | IDO1PPARGKMT2AMEN1TDP1 | |
| SCHEMBL21971206 | 0.73 | GAA (0.52) | KMT2AMEN1TDP1ALDH1A1CYP3A4 | |
| SCHEMBL31444289 | 0.72 | IDO1 (0.44) | IDO1PPARGKMT2ATDP1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025021189-A1 | OXYGEN-CONTAINING FUSED TRICYCLIC DERIVATIVE, AND PREPARATION METHOD THEREFOR AND USE THEREOF | 上海拓界生物医药科技有限公司 | 2025-01-30 | — | — | WO | disclosed |