SCHEMBL31347271

SCHEMBL31347271

CCOC(=O)c1ccc(-c2ccc(O)c(I)c2)cc1

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA1 P00915 5/20 0.59
CA2 P00918 5/20 0.59
CA12 O43570 4/20 0.59
CA7 P43166 4/20 0.59
CA9 Q16790 4/20 0.59
CA14 Q9ULX7 4/20 0.59
ESR1 P03372 2/20 0.57
ESR2 Q92731 1/20 0.56
HSD17B2 P37059 1/20 0.54
CYP1A2 P05177 2/20 0.50
LMNA P02545 1/20 0.50
CYP3A4 P08684 1/20 0.50
MAOA P21397 1/20 0.50
MEN1 O00255 1/20 0.47
KMT2A Q03164 1/20 0.47
STS P08842 1/20 0.47
PDK2 Q15119 1/20 0.46
KDM4E B2RXH2 1/20 0.46
NPC1 O15118 1/20 0.46
ALDH1A1 P00352 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL337806 0.87 ESR1 (0.72) CA1CA2CA12CA7CA9
SCHEMBL2785954 0.87 CA12 (0.55) CA1CA2CA12CA7CA9
SCHEMBL28659596 0.84 CA12 (0.63) CA1CA2CA12CA7CA9
SCHEMBL345875 0.82 CA1 (0.59) CA1CA2CA12CA7CA9
SCHEMBL6939271 0.82 CA12 (0.59) CA1CA2CA12CA7CA9
SCHEMBL30016425 0.82 CA1 (0.59) CA1CA2CA12CA7CA9
SCHEMBL1965326 0.82 CA1 (0.73) CA1CA2CA12CA7CA9
SCHEMBL16351874 0.82 CA1 (0.73) CA1CA2CA12CA7CA9
SCHEMBL9252178 0.81 MCL1 (0.62) CA1CA2CA12CA7CA9
SCHEMBL10607787 0.80 CA1 (0.61) CA1CA2CA12CA7CA9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119335104-A Method for detecting related substances in Qu Faluo-containing bulk drug 上海瑞替诺医药科技有限公司 2025-01-21 CN claimed
CN-119335104-A Method for detecting related substances in Qu Faluo-containing bulk drug 上海瑞替诺医药科技有限公司 2025-01-21 CN disclosed