Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 4/20 | 0.72 |
| ▸ | CA12 | O43570 | 6/20 | 0.72 |
| ▸ | CA1 | P00915 | 6/20 | 0.72 |
| ▸ | CA2 | P00918 | 6/20 | 0.72 |
| ▸ | CA7 | P43166 | 6/20 | 0.72 |
| ▸ | CA9 | Q16790 | 6/20 | 0.72 |
| ▸ | CA14 | Q9ULX7 | 6/20 | 0.72 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.64 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.58 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.51 |
| ▸ | MAOA | P21397 | 1/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.48 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.48 |
| ▸ | STS | P08842 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31347271 | 0.87 | CA1 (0.59) | ESR1CA12CA1CA2CA7 | |
| SCHEMBL1313506 | 0.86 | CA12 (0.72) | ESR1CA12CA1CA2CA7 | |
| SCHEMBL28417178 | 0.86 | CA12 (0.61) | ESR1CA12CA1CA2CA7 | |
| SCHEMBL2228061 | 0.84 | CA12 (0.59) | ESR1CA12CA1CA2CA7 | |
| SCHEMBL30410030 | 0.84 | CA12 (0.59) | ESR1CA12CA1CA2CA7 | |
| SCHEMBL39791 | 0.84 | CA12 (1.00) | ESR1CA12CA1CA2CA7 | |
| SCHEMBL29625511 | 0.84 | CA12 (1.00) | ESR1CA12CA1CA2CA7 | |
| SCHEMBL2785954 | 0.84 | CA12 (0.55) | ESR1CA12CA1CA2CA7 | |
| SCHEMBL7590031 | 0.83 | CA12 (0.57) | ESR1CA12CA1CA2CA7 | |
| SCHEMBL26586724 | 0.83 | ESR1 (0.63) | ESR1CA12CA1CA2CA7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210171883-A1 | ANTIVIRAL WIPER | FUJIFILM CORPORATION (JP) | 2021-06-10 | — | — | US | disclosed |
| US-20120129828-A1 | S1P1 RECEPTOR AGONISTS AND USE THEREOF | AMGEN INC. | 2012-05-24 | — | — | US | disclosed |
| US-8097652-B2 | AMPA receptor potentiators | ELI LILLY AND COMPANY (US) | 2012-01-17 | — | — | US | disclosed |
| US-8097652-B2 | AMPA receptor potentiators | ELI LILLY AND COMPANY (US) | 2012-01-17 | — | — | US | disclosed |
| US-8097652-B2 | AMPA receptor potentiators | ELI LILLY AND COMPANY (US) | 2012-01-17 | — | — | US | disclosed |
| US-7718815-B2 | Alpha-aminoamide derivatives useful in the treatment of lower urinary tract disorders | NEWRON PHARMACEUTICALS S.P.A. (IT) | 2010-05-18 | — | — | US | disclosed |
| US-20100010090-A1 | AMPA RECEPTOR POTENTIATORS | ELI LILLY AND COMPANY | 2010-01-14 | — | — | US | disclosed |
| US-20100010090-A1 | AMPA RECEPTOR POTENTIATORS | ELI LILLY AND COMPANY | 2010-01-14 | — | — | US | disclosed |
| US-20100010090-A1 | AMPA RECEPTOR POTENTIATORS | ELI LILLY AND COMPANY | 2010-01-14 | — | — | US | disclosed |
| WO-2009154780-A1 | S1P1 RECEPTOR AGONISTS AND USE THEREOF | AMGEN INC. (US) | 2009-12-23 | — | — | WO | disclosed |
| WO-2008073789-A1 | AMPA RECEPTOR POTENTIATORS | ELI LILLY AND COMPANY (US) | 2008-06-19 | — | — | WO | disclosed |
| US-20080132567-A1 | Alpha-Aminoamide Derivatives Useful in the Treatment of Lower Urinary Tract Disorders | NEWRON PHARMACUETICALS S.P.A (IT) | 2008-06-05 | — | — | US | disclosed |
| EP-1893597-A2 | AMPA RECEPTOR POTENTIATORS | ELI LILLY AND COMPANY (US) | 2008-03-05 | — | — | EP | disclosed |
| US-20070142441-A1 | AMPA receptor potentiators | ELI LILLY AND COMPANY | 2007-06-21 | — | — | US | disclosed |
| WO-2006132811-A2 | AMPA RECEPTOR POTENTIATORS | ELI LILLY AND COMPANY (US) | 2006-12-14 | — | — | WO | disclosed |
| WO-2005070405-A1 | ALPHA-AMINOAMIDE DERIVATIVES USEFUL IN THE TREATMENT OF LOWER URINARY TRACT DISORDERS | NEWRON PHARMACEUTICALS S.P.A. (IT) | 2005-08-04 | — | — | WO | disclosed |
| EP-1557166-A1 | Alpha-aminoamide derivatives useful in the treatment of lower urinary tract disorders | Newron Pharmaceuticals S.p.A. (IT) | 2005-07-27 | — | — | EP | disclosed |
| US-20040077654-A1 | Aryl piperidine and piperazine derivatives as inducers of ldl-receptor expression | SMITHKLINE BEECHAM CORPORATION | 2004-04-22 | — | — | US | disclosed |
| EP-1351936-A1 | ARYL PIPERIDINE AND PIPERAZINE DERIVATIVES AS INDUCERS OF LDL-RECEPTOR EXPRESSION | GLAXO GROUP LIMITED (GB) | 2003-10-15 | — | — | EP | disclosed |
| WO-2002055496-A1 | ARYL PIPERIDINE AND PIPERAZINE DERIVATIVES AS INDUCERS OF LDL-RECEPTOR EXPRESSION | GLAXO GROUP LIMITED (GB) | 2002-07-18 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120129828-A1 | S1P1 RECEPTOR AGONISTS AND USE THEREOF | S1PR1, S1PR5, S1PR2 | ESR1 1480/4885CA12 4575/4885CA1 4415/4885 |
| US-20070142441-A1 | AMPA receptor potentiators | GABRE, GRIN1, GRIK2 | ESR1 671/4885CA12 2225/4885CA1 522/4885 |
| US-20210171883-A1 | ANTIVIRAL WIPER | CGAS, PRKX, PDE4C | ESR1 4000/4885CA12 2396/4885CA1 2414/4885 |
| US-20100010090-A1 | AMPA RECEPTOR POTENTIATORS | GRIN1, GRIK2, GRIK1 | ESR1 1155/4885CA12 2984/4885CA1 856/4885 |
| US-20040077654-A1 | Aryl piperidine and piperazine derivatives as inducers of ldl-receptor expression | LDLR, NR1H2, NCOR1 | ESR1 1508/4885CA12 4853/4885CA1 4856/4885 |
| US-20080132567-A1 | Alpha-Aminoamide Derivatives Useful in the Treatment of Lower Urinary Tract Disorders | AADAT, BCAT2, DNPEP | ESR1 4120/4885CA12 1756/4885CA1 2532/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.