Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.43 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 6/20 | 0.42 |
| ▸ | MEN1 | O00255 | 4/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | KCNJ1 | P48048 | 1/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.41 |
| ▸ | CRHBP | P24387 | 2/20 | 0.39 |
| ▸ | CRHR2 | Q13324 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.38 |
| ▸ | SNCA | P37840 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1098058 | 0.86 | LMNA (0.46) | LMNAPTGS1PTGS2MAPTMEN1 | |
| SCHEMBL30386000 | 0.83 | TAAR1 (0.49) | LMNAPTGS1PTGS2MAPTMEN1 | |
| SCHEMBL29008515 | 0.83 | TAAR1 (0.49) | LMNAPTGS1PTGS2MAPTMEN1 | |
| SCHEMBL8008016 | 0.80 | PTGS1 (0.59) | LMNAPTGS1PTGS2MAPTMEN1 | |
| SCHEMBL309863 | 0.80 | LMNA (0.61) | LMNAPTGS1PTGS2MAPTMEN1 | |
| SCHEMBL3119714 | 0.80 | CYP19A1 (0.53) | PTGS2MAPK1ALDH1A1CYP19A1TSHR | |
| SCHEMBL10750758 | 0.80 | MAPT (0.50) | LMNAPTGS1PTGS2MAPTMEN1 | |
| SCHEMBL3508166 | 0.79 | LOXL2 (0.48) | LMNAPTGS1PTGS2MAPTMEN1 | |
| SCHEMBL15834453 | 0.79 | LMNA (0.46) | LMNAPTGS1PTGS2MAPTMEN1 | |
| SCHEMBL1098527 | 0.79 | MEN1 (0.47) | LMNAPTGS1PTGS2MAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119591621-A | Novel ecteinascidin derivatives, preparation method and application thereof, antibody drug conjugate and application thereof | 泰诚思(上海)生物医药有限公司 | 2025-03-11 | — | — | CN | disclosed |