Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR3C1 | P04150 | 1/20 | 0.50 |
| ▸ | PGR | P06401 | 1/20 | 0.50 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.50 |
| ▸ | AR | P10275 | 1/20 | 0.50 |
| ▸ | JAK1 | P23458 | 16/20 | 0.49 |
| ▸ | JAK2 | O60674 | 16/20 | 0.49 |
| ▸ | JAK3 | P52333 | 2/20 | 0.46 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31347584 | 0.91 | JAK1 (0.53) | JAK1JAK2KCNH2 | |
| SCHEMBL31347577 | 0.88 | JAK1 (0.47) | JAK1JAK2 | |
| SCHEMBL31347601 | 0.84 | JAK1 (0.53) | NR3C1PGRNR3C2ARJAK1 | |
| SCHEMBL31347578 | 0.84 | JAK1 (0.45) | JAK1JAK2 | |
| SCHEMBL30756867 | 0.82 | JAK1 (0.54) | JAK1JAK2KCNH2 | |
| SCHEMBL26987570 | 0.82 | JAK1 (0.54) | JAK1JAK2KCNH2 | |
| SCHEMBL31347560 | 0.82 | JAK1 (0.51) | JAK1JAK2KCNH2 | |
| SCHEMBL26993838 | 0.79 | JAK1 (0.47) | JAK1JAK2KCNH2 | |
| SCHEMBL30757116 | 0.78 | JAK1 (0.63) | JAK1JAK2KCNH2 | |
| SCHEMBL26987232 | 0.78 | JAK1 (0.63) | JAK1JAK2KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119403798-A | Novel compounds as GCN2 inhibitors, pharmaceutical compositions and uses thereof | 东亚ST 株式会社 | 2025-02-07 | — | — | CN | disclosed |