Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | JAK1 | P23458 | 17/20 | 0.47 |
| ▸ | JAK2 | O60674 | 15/20 | 0.47 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.44 |
| ▸ | CCNK | O75909 | 1/20 | 0.44 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.44 |
| ▸ | CDK2 | P24941 | 1/20 | 0.44 |
| ▸ | CDK9 | P50750 | 1/20 | 0.44 |
| ▸ | CDK12 | Q9NYV4 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31347584 | 0.91 | JAK1 (0.53) | JAK1JAK2 | |
| SCHEMBL31347540 | 0.88 | NR3C1 (0.50) | JAK1JAK2 | |
| SCHEMBL31347601 | 0.84 | JAK1 (0.53) | JAK1JAK2 | |
| SCHEMBL31347560 | 0.83 | JAK1 (0.51) | JAK1JAK2 | |
| SCHEMBL30756867 | 0.83 | JAK1 (0.54) | JAK1JAK2 | |
| SCHEMBL26987570 | 0.83 | JAK1 (0.54) | JAK1JAK2 | |
| SCHEMBL26993923 | 0.80 | JAK1 (0.63) | JAK1JAK2 | |
| SCHEMBL26993838 | 0.79 | JAK1 (0.47) | JAK1JAK2 | |
| SCHEMBL30757215 | 0.78 | JAK1 (0.60) | JAK1JAK2 | |
| SCHEMBL26993850 | 0.78 | JAK1 (0.60) | JAK1JAK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119403798-A | Novel compounds as GCN2 inhibitors, pharmaceutical compositions and uses thereof | 东亚ST 株式会社 | 2025-02-07 | — | — | CN | disclosed |