Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCNK | O75909 | 2/20 | 0.37 |
| ▸ | CDK12 | Q9NYV4 | 2/20 | 0.37 |
| ▸ | EIF2AK2 | P19525 | 2/20 | 0.36 |
| ▸ | HTR1A | P08908 | 2/20 | 0.35 |
| ▸ | HRH4 | Q9H3N8 | 2/20 | 0.35 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.35 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.35 |
| ▸ | OGA | O60502 | 1/20 | 0.35 |
| ▸ | IRAK4 | Q9NWZ3 | 2/20 | 0.34 |
| ▸ | PRKCI | P41743 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.33 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.33 |
| ▸ | MRGPRX1 | Q96LB2 | 1/20 | 0.33 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.33 |
| ▸ | CDK2 | P24941 | 1/20 | 0.33 |
| ▸ | CCNA1 | P78396 | 1/20 | 0.33 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31347585 | 0.94 | HTR1A (0.39) | CCNKCDK12HTR1AHRH4HRH3 | |
| SCHEMBL31347588 | 0.91 | CCNK (0.36) | CCNKCDK12HTR1AHRH4HRH3 | |
| SCHEMBL31347563 | 0.89 | HTR1A (0.40) | CCNKCDK12HTR1AOGAIRAK4 | |
| SCHEMBL31347566 | 0.89 | CCR4 (0.39) | CCNKCDK12HRH4HRH3OGA | |
| SCHEMBL31347571 | 0.88 | ALOX5AP (0.39) | CCNKCDK12HRH4HRH3OGA | |
| SCHEMBL30775184 | 0.79 | EGFR (0.38) | IRAK4 | |
| SCHEMBL31347576 | 0.78 | LDHA (0.35) | HRH4IRAK4PRKCIROCK2 | |
| SCHEMBL31347565 | 0.78 | EGFR (0.35) | MAPK14IRAK4 | |
| SCHEMBL30775237 | 0.77 | CHRM2 (0.37) | IRAK4PRKCIMEN1HTTKMT2A | |
| SCHEMBL18615430 | 0.76 | LRRK2 (0.39) | EIF2AK2HRH4HRH3MAPK14OGA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119403798-A | Novel compounds as GCN2 inhibitors, pharmaceutical compositions and uses thereof | 东亚ST 株式会社 | 2025-02-07 | — | — | CN | disclosed |