Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 1/20 | 0.67 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.67 |
| ▸ | CTSS | P25774 | 1/20 | 0.62 |
| ▸ | CTSK | P43235 | 1/20 | 0.62 |
| ▸ | GNPAT | O15228 | 1/20 | 0.57 |
| ▸ | PAM | P19021 | 1/20 | 0.55 |
| ▸ | REN | P00797 | 1/20 | 0.52 |
| ▸ | CTRB1 | P17538 | 2/20 | 0.50 |
| ▸ | TACR1 | P25103 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | THRB | P10828 | 1/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3134757 | 1.00 | CYP3A4 (0.67) | CYP3A4MAPK1CTSSCTSKGNPAT | |
| SCHEMBL24178197 | 0.88 | CYP3A4 (0.63) | CYP3A4MAPK1CTSKRENALDH1A1 | |
| SCHEMBL6319150 | 0.88 | MAPK1 (0.69) | CYP3A4MAPK1CTSSCTSKPAM | |
| SCHEMBL6529461 | 0.88 | MAPK1 (0.69) | CYP3A4MAPK1CTSSCTSKPAM | |
| SCHEMBL2089507 | 0.88 | MAPK1 (0.69) | CYP3A4MAPK1CTSSCTSKPAM | |
| SCHEMBL4372161 | 0.84 | CTSL (0.61) | CYP3A4MAPK1CTSSCTSKCTRB1 | |
| SCHEMBL6677690 | 0.83 | GNPAT (0.73) | CTSSCTSKGNPATPAM | |
| SCHEMBL5692056 | 0.83 | GNPAT (0.73) | CTSSCTSKGNPATPAM | |
| SCHEMBL1081111 | 0.83 | GNPAT (0.73) | CTSSCTSKGNPATPAM | |
| SCHEMBL27817100 | 0.83 | GNPAT (0.73) | CTSSCTSKGNPATPAM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100009927-A1 | Anti-Inflammatory and Anti-Allergy Extracts from Nettle | HERBALSCIENCE GROUP LLC (US) | 2010-01-14 | — | — | US | disclosed |
| EP-1223215-A1 | TRANSFORMANT PRODUCING SECONDARY METABOLITE MODIFIED WITH FUNCTIONAL GROUP AND NOVEL BIOSYNTHESIS GENES | MEIJI SEIKA KAISHA LTD. (JP) | 2002-07-17 | — | — | EP | disclosed |