Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2B | P41595 | 3/20 | 0.44 |
| ▸ | HTR2A | P28223 | 2/20 | 0.44 |
| ▸ | HTR2C | P28335 | 2/20 | 0.44 |
| ▸ | DRD2 | P14416 | 1/20 | 0.41 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.39 |
| ▸ | HTR1A | P08908 | 1/20 | 0.39 |
| ▸ | DRD3 | P35462 | 1/20 | 0.39 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.39 |
| ▸ | CETP | P11597 | 6/20 | 0.38 |
| ▸ | KDM1A | O60341 | 1/20 | 0.37 |
| ▸ | RCOR1 | Q9UKL0 | 1/20 | 0.37 |
| ▸ | SLC6A9 | P48067 | 2/20 | 0.37 |
| ▸ | PNMT | P11086 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31348125 | 1.00 | HTR2B (0.44) | HTR2BHTR2AHTR2CDRD2CHRM2 | |
| SCHEMBL31348260 | 0.83 | HSD17B2 (0.41) | DRD2GRIN2BCETPSLC6A9 | |
| SCHEMBL31348130 | 0.80 | HTR2C (0.47) | HTR2BHTR2AHTR2CDRD2CHRM2 | |
| SCHEMBL31348140 | 0.78 | DRD2 (0.55) | HTR2BHTR2AHTR2CDRD2CHRM2 | |
| SCHEMBL31348230 | 0.74 | SMYD3 (0.41) | HTR2AHTR2CDRD2HTR1ADRD3 | |
| SCHEMBL8604467 | 0.67 | DRD2 (0.49) | HTR2BHTR2AHTR2CDRD2CHRM2 | |
| SCHEMBL31348258 | 0.67 | PDE2A (0.40) | DRD2GRIN2B | |
| SCHEMBL31348112 | 0.67 | PDE2A (0.40) | DRD2GRIN2B | |
| SCHEMBL25004703 | 0.65 | HTR2C (0.59) | HTR2BHTR2AHTR2CDRD2CHRM2 | |
| SCHEMBL16350172 | 0.65 | HTR2C (0.59) | HTR2BHTR2AHTR2CDRD2CHRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025006982-A1 | POTENT AND SELECTIVE DOPAMINE D3 RECEPTOR ANTAGONISTS | THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) | 2025-01-02 | — | — | WO | disclosed |