Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 4/20 | 0.44 |
| ▸ | HDAC2 | Q92769 | 4/20 | 0.44 |
| ▸ | NAMPT | P43490 | 2/20 | 0.37 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.33 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.33 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.33 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.32 |
| ▸ | KDM1A | O60341 | 1/20 | 0.32 |
| ▸ | RYR2 | Q92736 | 1/20 | 0.31 |
| ▸ | CD38 | P28907 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.30 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28877856 | 0.84 | HDAC1 (0.42) | HDAC1HDAC2NAMPTPDK2NOTUM | |
| SCHEMBL26542931 | 0.84 | NOTUM (0.48) | HDAC1HDAC2NAMPTPDK2NOTUM | |
| SCHEMBL17624333 | 0.80 | HDAC1 (0.42) | HDAC1HDAC2NAMPTKDM1AALDH1A1 | |
| SCHEMBL26075398 | 0.79 | HDAC1 (0.39) | HDAC1HDAC2NAMPTPDK2KDM1A | |
| SCHEMBL25111471 | 0.73 | NOTUM (0.50) | NAMPTPDK2NOTUMALDH1A1 | |
| SCHEMBL14861328 | 0.73 | PDK2 (0.45) | HDAC1HDAC2NAMPTPDK2NOTUM | |
| SCHEMBL24176974 | 0.70 | HDAC1 (0.33) | HDAC1HDAC2KDM1A | |
| SCHEMBL31252184 | 0.69 | NAMPT (0.42) | NAMPTPDK2NOTUMRYR2CD38 | |
| SCHEMBL7095794 | 0.69 | NOTUM (0.35) | NOTUMRYR2ALDH1A1DPP8DPP9 | |
| SCHEMBL29640086 | 0.67 | HDAC2 (0.40) | HDAC1HDAC2ALDH1A1DPP8DPP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025006982-A1 | POTENT AND SELECTIVE DOPAMINE D3 RECEPTOR ANTAGONISTS | THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) | 2025-01-02 | — | — | WO | disclosed |