Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 12/20 | 0.69 |
| ▸ | DRD3 | P35462 | 9/20 | 0.69 |
| ▸ | ADRA1A | P35348 | 4/20 | 0.66 |
| ▸ | DRD4 | P21917 | 4/20 | 0.64 |
| ▸ | HTR1A | P08908 | 2/20 | 0.61 |
| ▸ | ADRA1D | P25100 | 2/20 | 0.61 |
| ▸ | ADRA1B | P35368 | 2/20 | 0.61 |
| ▸ | DRD1 | P21728 | 1/20 | 0.61 |
| ▸ | HTR2A | P28223 | 1/20 | 0.61 |
| ▸ | HTR2C | P28335 | 1/20 | 0.61 |
| ▸ | HTR2B | P41595 | 1/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8845095 | 1.00 | DRD2 (0.69) | DRD2DRD3ADRA1ADRD4HTR1A | |
| SCHEMBL31348246 | 0.85 | DRD3 (0.52) | DRD2DRD3ADRA1ADRD4HTR1A | |
| SCHEMBL19580052 | 0.81 | DRD2 (0.81) | DRD2DRD3ADRA1ADRD4HTR1A | |
| SCHEMBL9650872 | 0.79 | DRD2 (0.80) | DRD2DRD3ADRA1ADRD4HTR1A | |
| SCHEMBL14761722 | 0.79 | DRD2 (1.00) | DRD2DRD3ADRA1ADRD4HTR1A | |
| SCHEMBL8445675 | 0.79 | DRD2 (1.00) | DRD2DRD3ADRA1ADRD4HTR1A | |
| SCHEMBL3162960 | 0.78 | DRD2 (0.76) | DRD2DRD3DRD4 | |
| SCHEMBL10908587 | 0.78 | DRD2 (0.83) | DRD2DRD3ADRA1ADRD4HTR1A | |
| SCHEMBL13922058 | 0.78 | DRD2 (1.00) | DRD2DRD3ADRA1ADRD4HTR1A | |
| SCHEMBL8876209 | 0.78 | DRD2 (0.82) | DRD2DRD3ADRA1ADRD4HTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025006982-A1 | POTENT AND SELECTIVE DOPAMINE D3 RECEPTOR ANTAGONISTS | THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) | 2025-01-02 | — | — | WO | disclosed |