Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 12/20 | 0.80 |
| ▸ | DRD3 | P35462 | 10/20 | 0.80 |
| ▸ | DRD4 | P21917 | 7/20 | 0.80 |
| ▸ | HTR1A | P08908 | 4/20 | 0.74 |
| ▸ | ADRA1D | P25100 | 2/20 | 0.74 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.74 |
| ▸ | ADRA1B | P35368 | 2/20 | 0.74 |
| ▸ | HTR2A | P28223 | 3/20 | 0.71 |
| ▸ | HTR2C | P28335 | 1/20 | 0.71 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.71 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9653836 | 0.97 | DRD2 (0.75) | DRD2DRD3DRD4HTR1AADRA1D | |
| SCHEMBL14761722 | 0.89 | DRD2 (1.00) | DRD2DRD3DRD4HTR1AADRA1D | |
| SCHEMBL14761605 | 0.88 | DRD2 (0.98) | DRD2DRD3DRD4HTR1AADRA1D | |
| SCHEMBL14761584 | 0.86 | DRD2 (0.94) | DRD2DRD3DRD4HTR1AADRA1D | |
| SCHEMBL3086024 | 0.83 | DRD2 (1.00) | DRD2DRD3DRD4HTR1AADRA1D | |
| SCHEMBL17194866 | 0.83 | DRD2 (1.00) | DRD2DRD3DRD4HTR1AADRA1D | |
| SCHEMBL10950772 | 0.83 | DRD2 (0.98) | DRD2DRD3DRD4HTR1AADRA1D | |
| SCHEMBL6053607 | 0.83 | DRD2 (0.94) | DRD2DRD3DRD4HTR1AADRA1D | |
| SCHEMBL4527831 | 0.83 | DRD3 (1.00) | DRD2DRD3DRD4HTR1AADRA1D | |
| Bp-897 SCHEMBL26086545 | 0.82 | DRD2 (0.96) | DRD2DRD3DRD4HTR1AADRA1D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0496692-A1 | 2-Methoxyphenylpiperazine derivatives | FABRICA ESPANOLA DE PRODUCTOS QUIMICOS Y FARMACEUTICOS, S.A. (FAES) (ES) | 1992-07-29 | — | — | EP | claimed |