SCHEMBL31348864

SCHEMBL31348864

CCC(c1ccccc1)(C(C)O)N(C)C

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GRIN1 Q05586 6/20 0.46
GRIN2A Q12879 6/20 0.46
GRIN2D O15399 5/20 0.46
GRIN2C Q14957 5/20 0.46
GRIN2B Q13224 4/20 0.46
ALDH1A1 P00352 2/20 0.44
CYP2D6 P10635 1/20 0.44
CYP2C19 P33261 1/20 0.44
HSD17B10 Q99714 1/20 0.44
KCNN4 O15554 1/20 0.43
OPRM1 P35372 2/20 0.41
CACNA1F O60840 1/20 0.41
ABCB1 P08183 1/20 0.41
CYP2B6 P20813 1/20 0.41
DRD4 P21917 1/20 0.41
DRD3 P35462 1/20 0.41
OPRD1 P41143 1/20 0.41
OPRK1 P41145 1/20 0.41
CACNA1D Q01668 1/20 0.41
KCNH2 Q12809 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28625822 0.73 TSHR (0.37) GRIN1GRIN2AGRIN2DGRIN2CGRIN2B
SCHEMBL1534340 0.71 KCNN4 (0.50) GRIN1GRIN2AGRIN2DGRIN2CGRIN2B
SCHEMBL1534228 0.71 KCNN4 (0.50) GRIN1GRIN2AGRIN2DGRIN2CGRIN2B
SCHEMBL1534309 0.71 KCNN4 (0.50) GRIN1GRIN2AGRIN2DGRIN2CGRIN2B
SCHEMBL669382 0.70 OPRM1 (0.43) ALDH1A1OPRM1DRD4DRD3OPRD1
SCHEMBL2588173 0.70 OPRM1 (0.43) ALDH1A1OPRM1DRD4DRD3OPRD1
SCHEMBL28312127 0.69 GRIN1 (0.42) GRIN1GRIN2AGRIN2DGRIN2CGRIN2B
SCHEMBL27976218 0.69 CYP2C19 (0.44) GRIN1GRIN2AGRIN2DGRIN2CGRIN2B
Hydrochloric Acid SCHEMBL15109953 0.69 OPRM1 (0.42) ALDH1A1OPRM1DRD4DRD3OPRD1
SCHEMBL10535093 0.69 CYP2C19 (0.49) GRIN1GRIN2AGRIN2DGRIN2CGRIN2B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119059921-A Preparation process of trimebutine base 宿迁瑞星化学有限公司 2024-12-03 CN disclosed