SCHEMBL28625822

SCHEMBL28625822

CCC(c1ccccc1)(C(C)C)N(c1ccccc1)c1ccccc1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.37
CYP2D6 P10635 3/20 0.37
ALDH1A1 P00352 1/20 0.37
CYP2C19 P33261 1/20 0.37
HSD17B10 Q99714 1/20 0.37
GRIN1 Q05586 6/20 0.36
GRIN2A Q12879 6/20 0.36
GRIN2D O15399 5/20 0.36
GRIN2C Q14957 5/20 0.36
GRIN2B Q13224 4/20 0.36
KCNN4 O15554 2/20 0.35
KCNH2 Q12809 4/20 0.35
OPRK1 P41145 3/20 0.35
HTR2A P28223 2/20 0.35
ADRA1A P35348 2/20 0.35
ADRA2B P18089 1/20 0.35
ADRA2C P18825 1/20 0.35
SLC6A2 P23975 1/20 0.35
SLC6A4 P31645 1/20 0.35
SLC6A3 Q01959 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25952871 0.74 TAAR1 (0.40) TSHRCYP2D6ALDH1A1CYP2C19KCNN4
SCHEMBL27668560 0.74 CYP2D6 (0.38) TSHRCYP2D6ALDH1A1CYP2C19HSD17B10
SCHEMBL21534536 0.74 TAAR1 (0.40) TSHRCYP2D6ALDH1A1CYP2C19KCNN4
SCHEMBL31348864 0.73 GRIN1 (0.46) CYP2D6ALDH1A1CYP2C19HSD17B10GRIN1
SCHEMBL24399780 0.72 CYP2D6 (0.37) CYP2D6ALDH1A1CYP2C19HSD17B10KCNN4
SCHEMBL10325859 0.69 CYP2D6 (0.45) CYP2D6ALDH1A1CYP2C19HSD17B10GRIN1
SCHEMBL6284917 0.69 GRIN1 (0.44) CYP2D6ALDH1A1CYP2C19HSD17B10GRIN1
SCHEMBL18671994 0.69 KMT2A (0.39) TSHRCYP2D6ALDH1A1CYP2C19CYP1A2
SCHEMBL9579235 0.69 RIPK1 (0.42) CYP2D6ALDH1A1CYP2C19HSD17B10GRIN1
SCHEMBL3390152 0.69 RIPK1 (0.38) CYP2D6ALDH1A1CYP2C19KCNH2OPRK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113372631-A Rubber-plastic composite foaming material 钜奕科技有限公司 2021-09-10 CN disclosed