Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | PRKCA | P17252 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | NR2F2 | P24468 | 1/20 | 0.33 |
| ▸ | CES2 | O00748 | 1/20 | 0.32 |
| ▸ | CES1 | P23141 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | BRD4 | O60885 | 1/20 | 0.32 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.32 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.32 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8178098 | 0.77 | HSD17B10 (0.55) | HSD17B10CRBNLMNAALDH1A1L3MBTL1 | |
| SCHEMBL12435982 | 0.72 | CRBN (0.50) | CRBNLMNAALDH1A1CYP2C19L3MBTL1 | |
| SCHEMBL4712321 | 0.71 | — | — | |
| SCHEMBL27878299 | 0.71 | MTNR1A (0.50) | KDM4EALDH1A1CES2CES1NPC1 | |
| SCHEMBL8176560 | 0.70 | HSD17B10 (0.46) | HSD17B10CRBNLMNAALDH1A1NPC1 | |
| SCHEMBL935406 | 0.69 | CRBN (0.46) | CRBNKDM4EALDH1A1CYP2C19L3MBTL1 | |
| SCHEMBL23728065 | 0.67 | CRBN (0.44) | CRBNALDH1A1L3MBTL1NR2F2ITGB3 | |
| SCHEMBL935426 | 0.67 | KMT2A (0.50) | CRBNKDM4EALDH1A1L3MBTL1BRD4 | |
| SCHEMBL2127808 | 0.67 | CES2 (0.42) | HSD17B10ALDH1A1CES2CES1TSHR | |
| SCHEMBL8156241 | 0.67 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025051102-A1 | DEUTERATED TETRACYCLIC DERIVATIVE AND USE THEREOF | 浙江我武翼方药业有限公司 | 2025-03-13 | — | — | WO | disclosed |
| CN-119591611-A | Deuterated tetracyclic derivative and application thereof | 浙江我武翼方药业有限公司 | 2025-03-11 | — | — | CN | disclosed |