Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.52 |
| ▸ | MITF | O75030 | 2/20 | 0.52 |
| ▸ | MAPT | P10636 | 2/20 | 0.52 |
| ▸ | PAX8 | Q06710 | 2/20 | 0.52 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.43 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.43 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31349278 | 0.86 | POLB (0.57) | POLBALDH1A1MAPTNPSR1KDM4E | |
| SCHEMBL31349303 | 0.82 | POLB (0.56) | POLBALDH1A1MAPTNPSR1KDM4E | |
| SCHEMBL13219632 | 0.80 | POLB (0.64) | POLBALDH1A1MITFMAPTNPSR1 | |
| SCHEMBL31349287 | 0.80 | POLB (0.56) | POLBALDH1A1MAPTNPSR1KDM4E | |
| SCHEMBL31349325 | 0.79 | POLB (0.58) | POLBALDH1A1MITFMAPTPAX8 | |
| SCHEMBL31349324 | 0.76 | FAAH (0.58) | POLBMAPTKDM4E | |
| SCHEMBL31349260 | 0.75 | KDM4E (0.56) | POLBNPSR1KDM4EKMT2AMEN1 | |
| SCHEMBL13219626 | 0.75 | POLB (0.65) | POLBALDH1A1MAPTKDM4EKMT2A | |
| SCHEMBL31349289 | 0.75 | POLB (0.58) | POLBALDH1A1MITFMAPTPAX8 | |
| SCHEMBL31349286 | 0.75 | POLB (0.53) | POLBALDH1A1NPSR1KDM4EKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4743446-A1 | NITRO-CONTAINING COMPOUNDS THAT KILL MYCOBACTERIA | Board of Trustees of Michigan State University (US) | 2026-05-20 | — | — | EP | disclosed |
| WO-2025015066-A1 | NITRO-CONTAINING COMPOUNDS THAT KILL MYCOBACTERIA | BOARD OF TRUSTEES OF MICHIGAN STATE UNIVERSITY (US) | 2025-01-16 | — | — | WO | disclosed |