Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.56 |
| ▸ | POLB | P06746 | 1/20 | 0.54 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | TPSAB1 | Q15661 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | HTR1A | P08908 | 1/20 | 0.46 |
| ▸ | HTR7 | P34969 | 1/20 | 0.46 |
| ▸ | FAAH | O00519 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31349324 | 0.85 | FAAH (0.58) | KDM4EPOLBFAAH | |
| SCHEMBL13219626 | 0.83 | POLB (0.65) | KDM4EPOLBL3MBTL1MEN1KMT2A | |
| SCHEMBL31349325 | 0.81 | POLB (0.58) | KDM4EPOLBL3MBTL1NPSR1MEN1 | |
| SCHEMBL31349286 | 0.81 | POLB (0.53) | KDM4EPOLBNPSR1MEN1KMT2A | |
| SCHEMBL14190802 | 0.79 | KDM4E (0.76) | KDM4EHRH3TPSAB1TP53NPSR1 | |
| SCHEMBL31349303 | 0.78 | POLB (0.56) | KDM4EPOLBNPSR1KMT2A | |
| SCHEMBL31349278 | 0.76 | POLB (0.57) | KDM4EPOLBHRH3L3MBTL1NPSR1 | |
| SCHEMBL13219627 | 0.76 | POLB (0.70) | KDM4EPOLBL3MBTL1 | |
| SCHEMBL31349220 | 0.75 | POLB (0.56) | KDM4EPOLBHRH3NPSR1MEN1 | |
| SCHEMBL12443384 | 0.75 | ALDH1A1 (0.62) | KDM4EPOLBL3MBTL1NPSR1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4743446-A1 | NITRO-CONTAINING COMPOUNDS THAT KILL MYCOBACTERIA | Board of Trustees of Michigan State University (US) | 2026-05-20 | — | — | EP | disclosed |
| WO-2025015066-A1 | NITRO-CONTAINING COMPOUNDS THAT KILL MYCOBACTERIA | BOARD OF TRUSTEES OF MICHIGAN STATE UNIVERSITY (US) | 2025-01-16 | — | — | WO | disclosed |