Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.54 |
| ▸ | PPARG | P37231 | 1/20 | 0.42 |
| ▸ | PPARD | Q03181 | 1/20 | 0.42 |
| ▸ | PPARA | Q07869 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.39 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | SRPK1 | Q96SB4 | 1/20 | 0.38 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31349261 | 0.87 | SMN1; SMN2 (0.53) | POLBPPARGPPARDPPARAMEN1 | |
| SCHEMBL31349205 | 0.83 | SMN1; SMN2 (0.54) | POLBMEN1KMT2ALMNASMN1; SMN2 | |
| SCHEMBL31349219 | 0.83 | POLB (0.57) | POLBPPARDPPARAL3MBTL1SLC2A1 | |
| SCHEMBL31349227 | 0.82 | POLB (0.56) | POLBMEN1KMT2AL3MBTL1SMN1; SMN2 | |
| SCHEMBL31349264 | 0.82 | POLB (0.51) | POLBMEN1KMT2A | |
| SCHEMBL31349245 | 0.79 | POLB (0.55) | POLBMEN1KMT2AL3MBTL1LMNA | |
| SCHEMBL31349236 | 0.79 | POLB (0.53) | POLBPPARDPPARAMEN1KMT2A | |
| SCHEMBL31349291 | 0.78 | POLB (0.57) | POLBMEN1KMT2ASRPK1 | |
| SCHEMBL31349298 | 0.78 | POLB (0.57) | POLBMEN1KMT2AL3MBTL1LMNA | |
| SCHEMBL31349207 | 0.77 | SLC2A1 (0.59) | POLBMEN1KMT2ALMNASLC2A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4743446-A1 | NITRO-CONTAINING COMPOUNDS THAT KILL MYCOBACTERIA | Board of Trustees of Michigan State University (US) | 2026-05-20 | — | — | EP | disclosed |
| WO-2025015066-A1 | NITRO-CONTAINING COMPOUNDS THAT KILL MYCOBACTERIA | BOARD OF TRUSTEES OF MICHIGAN STATE UNIVERSITY (US) | 2025-01-16 | — | — | WO | disclosed |